ultrasound-assisted extraction of carnosic acid and rosmarinic acid using ionic liquid solution from rosmarinus officinalisultrasound-assisted提取鼠尾草酸和rosmarinic酸使用离子液体溶液从迷迭香属.pdfVIP
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ultrasound-assisted extraction of carnosic acid and rosmarinic acid using ionic liquid solution from rosmarinus officinalisultrasound-assisted提取鼠尾草酸和rosmarinic酸使用离子液体溶液从迷迭香属
Int. J. Mol. Sci. 2012, 13, 11027-11043; doi:10.3390/ijms130911027 OPEN ACCESS International Journal of Molecular Sciences ISSN 1422-0067 /journal/ijms Article Ultrasound-Assisted Extraction of Carnosic Acid and Rosmarinic Acid Using Ionic Liquid Solution from Rosmarinus officinalis Ge Zu †, Rongrui Zhang †, Lei Yang *, Chunhui Ma, Yuangang Zu *, Wenjie Wang and Chunjian Zhao State Engineering Laboratory for Bioresource Eco-Utilization, Northeast Forestry University, Harbin 150040, China; E-Mails: zygenefu@ 163.com (G.Z.); zhangrongrui1986@126.com (R.Z.); mchmchmchmch@163.com (C.M.); wjwang225@ (W.W.); zcjsj@163.com (C.Z.) † These authors contributed equally to this work. * Authors to whom correspondence should be addressed; E-Mails: ylnefu@163.com (L.Y.); zygnefu@163.com (Y.Z.); Tel.: +86-451-8219-1387 (Y.Z.); Fax: +86-451-8210-2082 (Y.Z.). Received: 4 June 2012; in revised form: 10 August 2012 / Accepted: 14 August 2012 / Published: 5 September 2012 Abstract: Ionic liquid based, ultrasound-assisted extraction was successfully applied to the extraction of phenolcarboxylic acids, carnosic acid and rosmarinic acid, from Rosmarinus officinalis . Eight ionic liquids, with different cations and anions, were investigated in this work and [C mim]Br was selected as the optimal solvent. Ultrasound 8 extraction parameters, including soaking time, solid–liquid ratio, ultrasound power
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