the global challenge of antimicrobial resistance insights from economic analysis抗菌素耐药性的全球挑战的见解从经济分析.pdfVIP

Int. J. Environ. Res. Public Health 2010, 7, 3141-3149; doi:10.3390/ijerph7083141 OPEN ACCESS International Journal of Environmental Research and Public Health ISSN 1660-4601 /journal/ijerph Article The Global Challenge of Antimicrobial Resistance: Insights from Economic Analysis Karen Eggleston 1,*, Ruifang Zhang 2 and Richard J. Zeckhauser 3 1 Shorenstein Asia-Pacific Research Center, Stanford University, 616 Serra Road, Encina Hall, Stanford, CA 94305, USA 2 Global Investment Research, Goldman Sachs International, Peterborough Court, 133 Fleet Street, London EC4A 2BB, UK; E-Mail: ruifang.zhang@ 3 John F. Kennedy School of Government, Harvard University, 79 John F. Kennedy Street, Cambridge, MA 02138, USA; E-Mail: richard_zeckhauser@ * Author to whom correspondence should be addressed; E-Mail: karene@; Tel.: + 1-650-723-9072; Fax: + 1-650-723-6530. Received: 24 June 2010; in revised form: 27 July 2010 / Accepted: 30 July 2010 / Published: 9 August 2010 Abstract: The prevalence of antimicrobial resistance (AR) limits the therapeutic options for treatment of infections, and increases the social benefit from disease prevention. Like an environmental resource, antimicrobials require stewardship. The effectiveness of an antimicrobial agent is a global public good. We argue for greater use of economic analysis as an input to policy discussion about