the genome of the polar eukaryotic microalga coccomyxa subellipsoidea reveals traits of cold adaptation极地真核生物的基因组microalga coccomyxa subellipsoidea揭示了冷适应的特征.pdfVIP

Blanc et al. Genome Biology 2012, 13:R39 /2012/13/5/R39 RESEARCH Open Access The genome of the polar eukaryotic microalga Coccomyxa subellipsoidea reveals traits of cold adaptation 1* 2 3 3 4 2 Guillaume Blanc , Irina Agarkova , Jane Grimwood , Alan Kuo , Andrew Brueggeman , David D Dunigan , 2 4 3 3 3 5 James Gurnon , Istvan Ladunga , Erika Lindquist , Susan Lucas , Jasmyn Pangilinan , Thomas Pröschold , 3 3 4 6 7 7 Asaf Salamov , Jeremy Schmutz , Donald Weeks , Takashi Yamada , Alexandre Lomsadze , Mark Borodovsky , Jean-Michel Claverie 1, Igor V Grigoriev3 and James L Van Etten2 Abstract Background: Little is known about the mechanisms of adaptation of life to the extreme environmental conditions encountered in polar regions. Here we present the genome sequence of a unicellular green alga from the division chlorophyta, Coccomyxa subellipsoidea C-169, which we will hereafter refer to as C-169. This is the first eukaryotic microorganism from a polar environment to have its genome sequenced. Results: The 48.8 Mb genome contained in 20 chromosomes exhibits significant synteny conservation with the chromosomes of its relatives Chlorella variabilis and Chlamydomonas reinhardtii. The order of the genes is highly reshuffled within synteny blocks, suggesting that intra-chromosomal rearrangements were more prevalent than inter-chromosomal rearrangements. Remarkably, Zepp retrotransposons occur in clusters of nested elements with strictly one cluster per chromosome