swedish population substructure revealed by genome-wide single nucleotide polymorphism data瑞典人口子结构揭示了全基因组单核苷酸多态性数据.pdfVIP

Swedish Population Substructure Revealed by Genome- Wide Single Nucleotide Polymorphism Data 1,2,3 1,2,3,4 5 6 7 Elina Salmela , Tuuli Lappalainen , Jianjun Liu , Pertti Sistonen , Peter M. Andersen , Stefan 8 9 10 ¨ 1 10 2,3,11,12 Schreiber , Marja-Liisa Savontaus , Kamila Czene , Paivi Lahermo , Per Hall , Juha Kere * 1 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland, 2 Department of Medical Genetics, University of Helsinki, Helsinki, Finland, ¨ 3 Folkhalsan Institute of Genetics, Helsinki, Finland, 4 Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, 5 Human Genetics, Genome Institute of Singapore, Singapore, Singapore, 6 Finnish Red Cross Blood Transfusion Service, Helsinki, Finland, 7 Department of Neurology, ˚ ˚ ˚ Umea University Hospital, University of Umea, Umea, Sweden, 8 Department of General Internal Medicine, Institute for Clinical Molecular Biology, Christian-Albrechts- University, Kiel, Germany, 9 Department of Medical Genetics, University of Turku, Turku, Finland, 10 Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, 11 Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden, 12 Clinical Research Centre, Karolinska University Hospital, Huddinge, Sweden Abstract The use of genome-wide single nucleot