soulamarin, a new coumarin from stem bark of calophyllum soulattri树皮soulamarin,一个新的干细胞香豆素属soulattri.pdfVIP

Molecules 2011, 16, 9721-9727; doi:10.3390/molecule OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article Soulamarin, a New Coumarin from Stem Bark of Calophyllum soulattri Gwendoline Cheng Lian Ee 1,*, Siau Hui Mah 1, Soek Sin Teh 1, Mawardi Rahmani 1, Rusea Go 2 1 and Yun Hin Taufiq-Yap 1 Department of Chemistry, Faculty of Science, University Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia 2 Department of Biology, Faculty of Science, University Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia * Author to whom correspondence should be addressed; E-Mail: gwen@.my. Received: 22 September 2011; in revised form: 13 October 2011 / Accepted: 4 November 2011 / Published: 23 November 2011 Abstract: The extracts of the stem bark of Calophyllum soulattri gave a new pyranocoumarin, soulamarin (1), together with five other xanthones caloxanthone B (2), caloxanthone C (3), macluraxanthone (4), trapezifolixanthone (5) and brasixanthone B (6) one common triterpene, friedelin (7), and the steroidal triterpene stigmasterol (8). The structures of these compounds were established based on spectral evidence (1D and 2D NMR). Keywords: soulamarin; pyranocoumarin; Calophyllum soulattri; Clusiaceae 1. Introduction The genus Calophyllum comprises over 200 species of trees and shrubs native to tropical Asia, East Africa, India and Australia. Calophyllum species have been used in traditional Chinese folk medicine for the trea