snailase preparation of ginsenoside m1 from protopanaxadiol-type ginsenoside and their protective effects against ccl4-induced chronic hepatotoxicity in mice从protopanaxadiol-type snailase制备人参皂苷m1人参皂苷和对老鼠ccl4-induced慢性肝毒性的保护作用.pdfVIP

下载本文档

1
0
约3.17万字
约 11页
2017-09-12 发布于上海
举报
版权申诉

snailase preparation of ginsenoside m1 from protopanaxadiol-type ginsenoside and their protective effects against ccl4-induced chronic hepatotoxicity in mice从protopanaxadiol-type snailase制备人参皂苷m1人参皂苷和对老鼠ccl4-induced慢性肝毒性的保护作用.pdf

1、有哪些信誉好的足球投注网站（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
7、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

snailase preparation of ginsenoside m1 from protopanaxadiol-type ginsenoside and their protective effects against ccl4-induced chronic hepatotoxicity in mice从protopanaxadiol-type snailase制备人参皂苷m1人参皂苷和对老鼠ccl4-induced慢性肝毒性的保护作用

Molecules 2011, 16, 10093-10103; doi:10.3390/molecules161210093 OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article Snailase Preparation of Ginsenoside M1 from Protopanaxadiol-Type Ginsenoside and Their Protective Effects Against CCl -Induced Chronic Hepatotoxicity in Mice 4 Wei Li 1,2,†, Ming Zhang 1,†, Yi-Nan Zheng 2, Jing Li 1, Ying-Ping Wang 3, Yun-Jing Wang 1, Jian Gu 1, Ying Jin 4, Hui Wang 4,* and Li Chen 1,* 1 Norman Bethune College of Medicine, Jilin University, Changchun 130021, China 2 College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China 3 Institute of Special Wild Economic Animals and Plant, CAAS, Jilin 132109, China 4 China-Japan Union Hospital, Jilin University, Changchun 130033, China † These authors contributed equally to this work and were considered co-first authors. * Authors to whom correspondence should be addressed; E-Mails: wanghu (H.W.); zhouweichen@ (L.C.); Tel.: +86-0431-8561-9922. Received: 21 October 2011; in revised form: 24 November 2011 / Accepted: 29 November 2011 / Published: 6 December 2011 Abstract: To investigate the protective effects of protopanaxadiol-type ginsenoside (PDG) and its metabolite ginsenoside M1 (G-M1) on carbon tetrachloride (CCl )-induced chronic 4 liver injury in ICR mice, we carried out conversion of protopanaxadiol-type ginsenosides to ginsenoside M1 using snailase. The optimum time for the conversi