small volume of hypertonic saline as the initial fluid replacement in experimental hypodynamic sepsis体积小的高渗盐水作为初始流体替代实验衰弱的脓毒症.pdfVIP

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small volume of hypertonic saline as the initial fluid replacement in experimental hypodynamic sepsis体积小的高渗盐水作为初始流体替代实验衰弱的脓毒症.pdf

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small volume of hypertonic saline as the initial fluid replacement in experimental hypodynamic sepsis体积小的高渗盐水作为初始流体替代实验衰弱的脓毒症

Available online /content/10/2/R62 Vol 10 No 2 Open Access Research Small volume of hypertonic saline as the initial fluid replacement in experimental hypodynamic sepsis Alejandra del Pilar Gallardo Garrido, Ruy Jorge Cruz Junior, Luiz Francisco Poli de Figueiredo and Maurício Rocha e Silva Research Division, Heart Institute (InCor), University of Sao Paulo School of Medicine, Sao Paulo, Brazil Corresponding author: Alejandra del Pilar Gallardo Garrido, alejandragg@.br Received: 22 Jan 2006 Revisions requested: 23 Feb 2006 Revisions received: 28 Feb 2006 Accepted: 17 Mar 2006 Published: 13 Apr 2006 Critical Care 2006, 10:R62 (doi:10.1186/cc4901) This article is online at: /content/10/2/R62 © 2006 Garrido et al., licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction We conducted the present study to examine the mO2ER). Widening of venous-arterial (approximately 15 effects of hypertonic saline solution (7.5%) on cardiovascular mmHg), portal-arterial (approximately 18 mmHg) and gastric function and splanchnic perfusion in experimental sepsis. mucosal-arterial (approximately 55 mmHg) pCO2 gradients were also observed. LR and HS infusion transiently improved Methods Anesthetized and mechanically ventilated mongrel systemic and regional blood flow. However, HS infus