antioxidant and anti-protease activities of diazepinomicin from the sponge-associated micromonospora strain rv115抗氧化剂和anti-protease活动的diazepinomicin sponge-associated rv115小单孢菌属菌株.pdfVIP

antioxidant and anti-protease activities of diazepinomicin from the sponge-associated micromonospora strain rv115抗氧化剂和anti-protease活动的diazepinomicin sponge-associated rv115小单孢菌属菌株.pdf

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antioxidant and anti-protease activities of diazepinomicin from the sponge-associated micromonospora strain rv115抗氧化剂和anti-protease活动的diazepinomicin sponge-associated rv115小单孢菌属菌株

Mar. Drugs 2012, 10, 2208-2221; doi:10.3390/m OPEN ACCESS Marine Drugs ISSN 1660-3397 /journal/marinedrugs Article Antioxidant and Anti-Protease Activities of Diazepinomicin from the Sponge-Associated Micromonospora Strain RV115 Usama Ramadan Abdelmohsen 1,†,*, Matthias Szesny 2, Eman Maher Othman 3,‡, 4 2 3 1 Tanja Schirmeister , Stephanie Grond , Helga Stopper and Ute Hentschel 1 Julius-von-Sachs-Institute for Biological Sciences, University of Würzburg, Julius-von-Sachs-Platz 3, Würzburg 97082, Germany; E-Mail: ute.hentschel@uni-wuerzburg.de 2 Institute of Organic Chemistry, Eberhard-Karls-Universität, Auf der Morgenstelle 18, Tübingen 72076, Germany; E-Mails: matthias.szesny@uni-tuebingen.de (M.S.); stephanie.grond@uni-tuebingen.de (S.G.) 3 Department of Toxicology, University of Würzburg, Würzburg 97078, Germany; E-Mails: eman@toxi.uni-wuerzburg.de (E.M.O.); stopper@toxi.uni-wuerzburg.de (H.S.) 4 Institute of Pharmacy and Biochemistry, University of Mainz, Staudinger Weg 5, Mainz 55128, Germany; E-Mail: schirmei@uni-mainz.de † Permanent address: Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia 61519, Egypt. ‡ Permanent address: Department of Analytical Chemistry, Faculty of Pharmacy, Minia University, Minia 61519, Egypt. * Author to whom correspondence should be addressed; E-Mail: usama.ramadan@uni-wuerzburg.de; Tel.: +49-931-318-0297; Fax: +49-931-888-6235. Received: 24 July 2012; in revised form: 6 September 2012 / Accept

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