a specific oligodeoxynucleotide promotes the differentiation of osteoblasts via erk and p38 mapk pathways一个特定oligodeoxynucleotide促进成骨细胞的分化通过erk和p38 mapk通路.pdfVIP
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a specific oligodeoxynucleotide promotes the differentiation of osteoblasts via erk and p38 mapk pathways一个特定oligodeoxynucleotide促进成骨细胞的分化通过erk和p38 mapk通路
Int. J. Mol. Sci. 2012, 13, 7902-7914; doi:10.3390/ijm
OPEN ACCESS
International Journal of
Molecular Sciences
ISSN 1422-0067
/journal/ijms
Article
A Specific Oligodeoxynucleotide Promotes the Differentiation of
Osteoblasts via ERK and p38 MAPK Pathways
1 2 1 1 2 3 4
Xu Hou , Yuqin Shen , Chao Zhang , Liru Zhang , Yanyan Qin , Yongli Yu , Liying Wang
and Xinhua Sun 1,*
1 Department of Orthodontics, School of Stomatology, Jilin University, 1500 Qinghua Road,
Changchun 130021, China; E-Mails: houxu@ (X.H.);
zc11@ (C.Z.); lrzhang10@ (L.Z.)
2 Department of Periodontics, School of Stomatology, Jilin University, 1500 Qinghua Road,
Changchun 130021, China; E-Mails: shenyq@ (Y.S.); yyqin09@ (Y.Q.)
3 Department of Immunology, Medical College of Norman Bethune, Jilin University,
Changchun 130021, China; E-Mail: ylyu@
4 Department of Molecular Biology, Medical College of Norman Bethune, Jilin University,
Changchun 130021, China; E-Mail: wlying@
* Author to whom correspondence should be addressed; E-Mail: sunxinh@;
Tel.: +86-431 Fax: +86-431
Received: 10 May 2012; in revised form: 11 May 2012 / Accepted: 15 June 2012 /
Published: 25 June 2012
Abstract: A specific oligodeoxynucleotide (ODN), ODN MT01, was found to have
positive effects on the proliferation and activation of the osteoblast-like
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