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幼年性结肠息肉与幼年性结肠息肉病(Juvenile polyposis coli and juvenile polyposis coli)
幼年性结肠息肉与幼年性结肠息肉病(Juvenile polyposis coli and juvenile polyposis coli) Juvenile polyposis coli and juvenile polyposis coli 2009-11-17 Zhang Shutian Yu Zhonglin 1 juvenile polyps Juvenile polyps are hamartoma polyps, the so-called hamartoma refers to normal tissue dysplasia and tumor like change, it and inflammatory polyps, hyperplastic polyps are non neoplastic polyps. In 1957, it was named Juvenile Polyp by Horrilleno. Horrilleno et al reported that juvenile polyps account for 0.075% of all pediatric hospitalizations and are characterized by cystic cystic dilatation, which is called retention polyps. 1.1 the histology of young polyps is cystic dilatation, filled with mucus and neutrophils. The cells in the stroma are rich in lymphocytes, neutrophils and eosinophils. A gland polyp without atypia, interstitial hemorrhage, capillary congestion, epithelial surface often fall off, the clinical symptoms were hematochezia, endoscopy for redness of the polyp. Unlike J-Ps syndrome, juvenile polyps do not see dendritic hyperplasia in the muscularis mucosae, nor can it be seen that the muscularis mucosa of the adenoma is involved in the polyp and is therefore a polyp that is naturally detached. Roth (1963) reported that the incidence of juvenile polyps in 4 and 18~22 years old showed two peaks, 16 years old before the onset of less than half, accounting for 19% to 62%, so far this understanding has not changed. Juvenile polyps in adults and the elderly have increased due to widespread screening and endoscopic polypectomy. The ratio of male to female is male female. 70% to 80% are single polyps, there are also multiple, and multiple should be identified with juvenile polyposis, 80% located in the rectum, sigmoid colon. 1.2. Etiology: hamartoma of the stroma of the lamina propria; inflammation leading to obstruction of the opening of the gland duct. Classification of multiple cases into hamartoma, so it is likely to be caused by some inflammation on the basis of hamartoma. 1.3
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