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干细胞概述-生命科学.PDF

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干细胞概述-生命科学

18 4 Vol. 18, No. 4 2006 8 Chinese Bulletin of Life Sciences Aug., 2006 1004-0374(2006)04-0313-05 · · 410078 Q 83 1 A Summary of stem cells LIN Ge, LU Guang-Xiu* (Institute of Reproductive and Stem Cell Engineering, Central South University, National Engineering and Research Center of Human Stem Cell, Changsha 410078, China) Abstract: Stem cells are specialized cell types in the embryonic and adult tissue. They have the ability of long term self-renewal and could give rise to various terminal differentiated cell types in specific condition. Stem cells from different origin have different differentiation potential. Embryonic stem cells derived from early pre- implantation embryo have the capacity to differentiate into all cell types in the body and could infinitely proliferate in vitro, which are considered to be one of the most valuable stem cells for future clinical application and research purpose. Adult stem cells exist in various adult tissues and organs and play a role in maintaining the structural and functional homeostasis of the body. Recent researches on the plasticity of adult stem cells and evidences of existence of pluripotent stem cells in the adult tissues broaden our view on the differentiation potential of adult stem cells. The ability of