第二十九章 组胺和组胺受体阻滞药（The twenty-ninth chapter is histamine and histamine receptor blocking drugs）.docVIP

第二十九章 组胺和组胺受体阻滞药（The twenty-ninth chapter is histamine and histamine receptor blocking drugs） The twenty-ninth chapter, histamine and histamine receptor blocker release date: 2008-2-18 browsing times: 1267, this information needs to register and log in to download! Username, password, password, password back - youre not registered yet? Please register your account. The balance is RMB. The balance is insufficient. Please recharge it. Your account balance is $. The purchase will be deducted from your account and the cost will be $0. Station data unified decompression password: 100 content introduction, twenty-ninth chapter histamine and histamine receptor block drugs Be familiar with the pharmacological characteristics of H1 receptor blockers. To be familiar with the pharmacological characteristics of H2 receptor blockers in clinical practice. Histamine (histamine) is an active substance widely found in human tissues. Histamine is mainly contained in mast cells and basophils. Therefore, histamine levels in the skin, bronchial mucosa and intestinal mucosa with more mast cells were higher, and higher concentrations were also found in cerebrospinal fluid. Histamine in mast cell granules is often associated with proteins, and physical or chemical stimuli can cause mast cells to degranulation and cause histamine release. Histamine and target cell specific receptor binding and biological effects; such as small arteries, veins and capillaries, decrease blood pressure and even shock; increase the heart rate and cardiac contractility, inhibition of atrioventricular excitement; smooth muscle, cause bronchospasm, gastrointestinal colic; stimulate the stomach cells, cause gastric acid secretion. Histamine receptors are H1, H2, and H3 subtypes. The receptor function of each subtype is shown in table 29-1. The clinical application of histamine has been gradually reduced, but its receptor blocking agents are of great value in clinical practice. Histamine receptor distribution and ef