第二十一单元免疫缺陷性疾病（Twenty-first unit immunodeficiency disease）.docVIP

下载本文档

2
0
约6.91千字
约 10页
2017-09-02 发布于河南
举报
版权申诉

第二十一单元免疫缺陷性疾病（Twenty-first unit immunodeficiency disease）.doc

1、有哪些信誉好的足球投注网站（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
7、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

第二十一单元免疫缺陷性疾病（Twenty-first unit immunodeficiency disease）

第二十一单元免疫缺陷性疾病（Twenty-first unit immunodeficiency disease） Twenty-first unit immunodeficiency disease Concept: immunodeficiency disease (IDD) is the innate immune system hypoplasia or acquired damage to immune cell development, proliferation and differentiation, metabolic abnormalities, immune dysfunction and lead to the emergence of the clinical syndrome. According to etiology, primary immunodeficiency disease (PIDD) and acquired immunodeficiency disease (SIDD) can be divided into two categories. Features: easy recurrence and persistent infection. Malignant tumor is easy to happen. Concomitant autoimmune disease. There is genetic predisposition. I. concept Primary immunodeficiency disease is a disease caused by immune system abnormalities, genetic abnormalities, or congenital immune system disorders resulting from immune dysfunction. Two, common diseases Classification diseases, immunodeficiency, pathogenesis, clinical features B cell Deficiency disease X linked non gamma globulin (XLA) Immature B cell BtK defect Extracellular bacteria, viral infections Selective IgA defect Low or no IgA Undetermined respiratory tract infection Sex linked high IgM syndrome (XHM) No Ig class conversion CD40L defect Infection by extracellular bacteria T cell Deficiency DiGeorge syndrome T and B cell development Thymic and multiple organ development disorder Recurrent intracellular parasite infection TCR signaling disorder T cell response deficit CD3 epsilon or gamma chain defect Infection by intracellular parasites Combined type exemption Epidemic disease Severe combined immune deficiency disease (SCID) 1.X- linked recessive inheritance SCID No T cell IL-2R gamma (gamma C) strand deletion Prone to repeated infection 2 autosomal recessive inheritance SCID Adenylate deaminase (ADA) and purine nucleotide phosphorylase (PNP) deficiency Disorders of T and B cell metabolism ADA and PNP defects Prone to repeated serious infection II. HLA class II molecular expression defect (naked lymphocyt