真核生物基因表达的调控（Regulation of gene expression in eukaryotes）.docVIP

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真核生物基因表达的调控（Regulation of gene expression in eukaryotes）.doc

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真核生物基因表达的调控（Regulation of gene expression in eukaryotes）

真核生物基因表达的调控（Regulation of gene expression in eukaryotes） Regulation of gene expression in eukaryotes 10.1 the characteristics and types of gene expression regulation in eukaryotes Characteristics of gene expression regulation in eukaryotes The regulation system of prokaryotes is to create high growth conditions in a particular environment for the cells, or the cells in damage, repair as soon as possible, so that the switch of gene expression in prokaryotes is often regulated by transcription initiation control. The most significant feature of eukaryotic gene regulation can activate specific genes in a specific time and specific cells, so as to realize the target, orderly and irreversible differentiation and development process, and biological tissues and organs to maintain normal function in a certain range of environmental conditions. Similarities between prokaryotic gene expression regulation and prokaryotic expression in eukaryotes: Gene expression has both transcriptional level and post transcriptional regulation, and the regulation of transcription level is the most important; There are many regulatory elements in the upstream and downstream of the structural gene and even the internal, and the transcription of genes depends on the binding of specific protein factors to these regulatory components. The difference between prokaryotic expression and regulation of eukaryotic gene expression: 1, eukaryotic gene expression regulation is more: transcription and translation intervals, a variety of prokaryotes do not have regulatory mechanisms; complex development of individuals, genes regulating the specific expression of the mechanism. 2. The change of eukaryotic active chromosome structure can regulate gene expression: DNA topological structure change, DNA base modifier change and histone change; 3, positive regulation is predominant, and a eukaryotic gene usually has multiple regulatory sequences and requires multiple activators. Two. The types of gene expression r