a new body shape index predicts mortality hazard independently of body mass index一个新的身体形状指数预测死亡率风险独立于身体质量指数.pdfVIP

A New Body Shape Index Predicts Mortality Hazard Independently of Body Mass Index 1 2 Nir Y. Krakauer *, Jesse C. Krakauer 1 Department of Civil Engineering, The City College of New York, New York, New York, United States of America, 2 Middletown Medical, Middletown, New York, United States of America Abstract Background: Obesity, typically quantified in terms of Body Mass Index (BMI) exceeding threshold values, is considered a leading cause of premature death worldwide. For given body size (BMI), it is recognized that risk is also affected by body shape, particularly as a marker of abdominal fat deposits. Waist circumference (WC) is used as a risk indicator supplementary to BMI, but the high correlation of WC with BMI makes it hard to isolate the added value of WC. Methods and Findings: We considered a USA population sample of 14,105 non-pregnant adults (age §18) from the National Health and Nutrition Examination Survey (NHANES) 1999–2004 with follow-up for mortality averaging 5 yr (828 deaths). We developed A Body Shape Index (ABSI) based on WC adjusted for height and weight: WC ABSI : : BMI2=3height1=2 ABSI had little correlation with height, weight, or BMI. Death rates increased approximately exponentially with above average baseline ABSI (overall regression coefficient of z33% per standard deviation of ABSI [95% confidence interval: z20%– z48%]), whereas elevated death rates were found for both high and low values of BMI and WC. 22% (8%–41%) of the population mortality hazard was attributable to high ABSI, compared to 15% (3%–30%) for BMI a