有哪些信誉好的足球投注网站a challenge to the ancient origin of sivagm based on african green monkey mitochondrial genomes一个挑战古老的起源sivagm基于非洲绿猴线粒体基因组.pdfVIP
- 1、有哪些信誉好的足球投注网站（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
a challenge to the ancient origin of sivagm based on african green monkey mitochondrial genomes一个挑战古老的起源sivagm基于非洲绿猴线粒体基因组
A Challenge to the Ancient Origin of SIVagm Based on African Green Monkey Mitochondrial Genomes * Joel O. Wertheim , Michael Worobey Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona, United States of America While the circumstances surrounding the origin and spread of HIV are becoming clearer, the particulars of the origin of simian immunodeficiency virus (SIV) are still unknown. Specifically, the age of SIV, whether it is an ancient or recent infection, has not been resolved. Although many instances of cross-species transmission of SIV have been documented, the similarity between the African green monkey (AGM) and SIVagm phylogenies has long been held as suggestive of ancient codivergence between SIVs and their primate hosts. Here, we present well-resolved phylogenies based on full- length AGM mitochondrial genomes and seven previously published SIVagm genomes; these allowed us to perform the first rigorous phylogenetic test to our knowledge of the hypothesis that SIVagm codiverged with the AGMs. Using the Shimodaira–Hasegawa test, we show that the AGM mitochondrial genomes and SIVagm did not evolve along the same topology. Furthermore, we demonstrate that the SIVagm topology can be explained by a pattern of west-to-east transmission of the virus across existing AGM geographic ranges. Using a relaxed molecular clock, we also provide a date for the most recent common ancestor of the AGMs at approximately 3 million years ago. This study substantially weakens the theory of ancient SIV infection followed by codivergence with its primate hosts. Citation: Wertheim JO, Worobey M (2007) A challenge to the ancient origin of SIVagm based on African green monkey mitochondrial genomes. PLoS Pathog 3(7): e95. doi:10. 1371/journal.ppat.0030095 Introduction common ancestor more recently with every member of its
您可能关注的文档
- (a)symmetric stem cell replication and cancer(一)对称复制干细胞和癌症.pdf
- 1,25-dihydroxyvitamin d3 promotes a sustained lps-induced nf-κb-dependent expression of cd55 in human monocytic thp-1 cells1,25-dihydroxyvitamin d3促进持续lps-induced nf-κb-dependent人类单核细胞的表达cd55 thp-1细胞.pdf
- 2nd international external quality control assessment for the molecular diagnosis of dengue infections第二国际的外部质量控制评估的分子诊断登革热感染.pdf
- 1,25-dihydroxyvitamin d3 inhibits the differentiation and migration of th17 cells to protect against experimental autoimmune encephalomyelitis1,25-dihydroxyvitamin d3抑制th17细胞的分化和迁移,防止实验性自身免疫性脑脊髓炎.pdf
- 2,4-diaminopyrimidines as potent inhibitors of trypanosoma brucei and identification of molecular targets by a chemical proteomics approach2,4-diaminopyrimidines强有力的抑制剂的锥虫属brucei化学蛋白质组学和分子靶点的识别方法.pdf
- 1+1？=？3 a fusion of 2 enzymes in the methionine salvage pathway of tetrahymena thermophila creates a trifunctional enzyme that catalyzes 3 steps in the pathway1 + 1 = 3融合2蛋氨酸救助途径的酶四膜虫thermophila创建一个三功能性的酶,这种酶催化途径3步骤.pdf
- 3, 3′5 triiodo l thyronine induces apoptosis in human breast cancer mcf-7cells, repressing smp30 expression through negative thyroid response elements3、3u20325 l三碘甲状腺原氨酸人类乳腺癌mcf-7cells发生凋亡,抑制smp30表达式通过负甲状腺响应元素.pdf
- 3′utr-mediated gene silencing of the mixed lineage leukemia (mll) gene3u2032utr-mediated基因沉默的混合血统白血病mll基因.pdf
- 3d active stabilization system with sub-micrometer resolution3 d与sub-micrometer决议主动稳定系统.pdf
- (s)-α-chlorohydrin inhibits protein tyrosine phosphorylation through blocking cyclic amp - protein kinase a pathway in spermatozoa(s)-α-chlorohydrin抑制蛋白质酪氨酸磷酸化通过阻断环腺苷酸蛋白激酶精子的途径.pdf
- a circadian clock in antarctic krill an endogenous timing system governs metabolic output rhythms in the euphausid species euphausia superba一个内源性生物钟在南极磷虾计时系统控制代谢产出节奏euphausid物种euphausia superba.pdf
- a chip-seq benchmark shows that sequence conservation mainly improves detection of strong transcription factor binding siteschip-seq基准显示序列保护主要提高了检测强劲的转录因子结合位点.pdf
- a cis-acting diversification activator both necessary and sufficient for aid-mediated hypermutationcis-acting多样化活化剂必要和足够aid-mediated hypermutation.pdf
- a clinical prediction rule for histological chorioamnionitis in preterm newborns组织学绒毛膜羊膜炎的临床预测规则早产新生儿.pdf
- a clear view of mycobacterial infection清晰可见的分枝杆菌感染.pdf
- a clinical diagnostic model for predicting influenza among young adult military personnel with febrile respiratory illness in singapore临床诊断模型来预测流感在年轻成人军事人员在新加坡发热呼吸道疾病.pdf
- a candidate approach implicates the secreted salmonella effector protein spvb in p-body disassembly候选人方法引起沙门氏菌分泌效应蛋白spvb p-body拆卸.pdf
- a circadian clock in the olfactory bulb anticipates feeding during food anticipatory activity嗅球的生物钟预计喂养在食品先行活动.pdf
- a claudin-9–based ion permeability barrier is essential for hearingclaudin-9-based离子通透性屏障对听力至关重要.pdf
- a cis-regulatory signature for chordate anterior neuroectodermal genes脊索动物的基因签名前neuroectodermal基因.pdf
文档评论（0）