几种重要植物次生代谢防御反应物质_省略_物合成途径及分子调控机制研究进.pdfVIP

生 物 技 术 通 讯 LETTERS IN BIOTECHNOLOGY Vol.24 No.2 Mar., 2013 285 doi: 10.3969/j.issn. 1009-0002.2013.02.033 综 述 几种重要植物次生代谢防御反应物质的生物合成途径及 分子调控机制研究进展 1 2 2 1 1 杨欣 ，徐艳红 ，魏建和 ，刘娟 ，张岩 1. 佳木斯大学 药学院，黑龙江 佳木斯 154007； 2. 中国医学科学院/ 北京协和医学院 药用植物研究所，北京 100193 ［摘要］ 参与植物防御反应相关的次生代谢产物主要有酚类、萜类和生物碱类。近几年，随着转录组学、蛋白组学及 新的分子生物学技术的广泛应用，极大地推进了植物次生代谢防御反应物质调控机制的研究进展。我们从这几类次 生代谢物质的合成途径及其参与植物防御反应的分子调控机制两大方面进行概述，重点介绍这三类具有防御作用的 次生代谢产物的生物合成途径、参与介导植物防御反应的相关信号分子及其转录调控机制，为正确认识植物次生代 谢防御反应提供理论依据。 ［关键词］ 次生代谢；防御反应；合成途径；调控机制；植物 ［中图分类号］ Q945 ［文献标识码］ A ［文章编号］ 1009-0002 （2013 ）02-0285-05 Advances on the Biosynthesis Pathways and Molecular Regulation Mechanism of Several Important Defensive Substances in Plant Sec⁃ ondary Metabolism 1 2 2 1 1 YANG Xin , XU Yan-Hong *, WEI Jian-He , LIU Juan , ZHANG Yan 1. College of Pharmacy, Jiamusi University, Jiamusi 154007; 2. Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences Peking Union Medical College, Beijing 100193; China *Corresponding author, E-mail: xvyanhong99@163.com ［Abstract］ Phenols, terpenoids and alkaloids are the main secondary metabolites which are involved in plant de⁃ fense response. In recent years, the research on the regulation mechanism of plant secondary metabolism and de⁃ fense response was greatly promoted along with the wide application of transcriptome, proteome and new molecular biology technology. Here, we summarized the progresses of the three kinds of secondary metabolites from two as⁃ pects, including their biosynthesis and regulation mechanisms, and highlight the biosynthesis pathways, signal mole⁃ cules involved in defense responses and their regulation mechanism. This review will p