30860例HBsAg阴性人群血清抗-HBs和抗-HBc检测结果回顾性分析.docVIP

30860例HBsAg阴性人群抗-HBs抗-HBc检测结果回顾性分析 王强1,2△，蔡艳娟1,2，杜琴1,2，王东升2，汪光蓉1,2，2，凡瞿明2，唐中1,2，张国元1,2( （川北医学院：1医学检验系，2附属医院检验科，四川 南充，637000） 摘要：目的 分析HBsAg阴性人群血清抗-HBs抗-HBc的检出情况。方法 收集我院门诊及住院HBsAg阴性人群血清抗-HBs抗-HBc定量检测结果及资料共30860份，对抗-HBs抗-HBc在不同年龄段和不同性别人群中的检出情况进行回顾性分析。 结果 抗-HBs、抗-HBs≥100IU/L和抗-HBc的检出率分别为70.84%、37.0%和61.4%。其中男性抗-HBs和抗-HBs≥100IU/L的检出率（%和%）均低于女性（%和%）男性抗-HBc的检出率（%）高于女性（%）（χ2，0.001）。不同年龄抗-HBs、抗-HBs≥100IU/L抗-HBc抗-HBs抗-HBc抗-HBs抗-HBc抗-HBs抗-HBc的检出率之间差异均有统计学意义（χ2值分别为140.9、728.6、6148.65，均0.01）抗-HBs和抗-HBs≥100IU/L的检出率分别以1~0岁和1~90岁最抗-HBc抗-HBs抗-HBc的检出率随年龄的降低而逐渐减低，从41岁的74.33%逐渐减低到1~10岁的2.9%和0.00%。抗-HBs抗-HBc抗-HBs抗-HBc的检出率随年龄的降低而逐渐，从41岁的%和11.51%逐渐到1~10岁的%和37.25%。 结论 抗-HBs抗-HBc了解抗-HBs抗-HBc的流行病学资料对乙肝具有重要意义。 关键词：乙肝表面抗原；乙肝表面抗体；乙肝核心抗体；回顾性分析HBsAg negtive people Wang Qiang1,2, Cai Yan-juan2, Du Qin2, Wang Dong-sheng2, Wang Guang-rong1,2, Lu Xiao-lan2 , Fan QU-ming2, Tang Zhong1,2, Zhang Guo-yuan1,2 (1College of Laboratory Medicine, 2Department of Laboratory Medicine, Affiliated Hospital, North Sichuan Medical college, Nanchong Sichuan, 637000, China) Abstract: Objective To investigate the detection rate of Anti-HBs and Anti-HBc in Hepatitis B virus surface antigen negative people. Methods 30860 clinical datas and the quantitative results of Anti-HBs and Anti-HBc in Hepatitis B virus surface antigen negative people were collected from our hospital. The detection rate of Anti-HBs and Anti-HBc were evaluated in different age and sex groups. Results Among 30860 HBsAg negative people, the detection rate of Anti-HBs, Anti-HBs≥100IU/L and Anti-HBc were 70.84%、37.0% and 61.41% respectively. The differences were statistically significant between male to female with the detection rate of Anti-HBs, Anti-HBs≥100IU/L and Anti-HBc(69.77%/71.94%, 34.37%/39.81% and 67.16%/55.52%, male/female; Chi-square values were 17.53, 97.74 and 441.10 respectively, all P0.001). The detection rate of Anti-HBs, Anti-HBs≥100IU/L, Anti-HBc, “Anti-HBs positive and Anti-HBc negtive”, “Anti-HBs negtive and Anti-HBc positiv