不同程度的慢性阻塞性肺疾病患者合并 心血管疾病及其危险因.PDFVIP

中国呼吸与危重监护杂志 2017年7月第16卷第4期 • 1 •   ·论　　著· 不同程度的慢性阻塞性肺疾病患者合并 心血管疾病及其危险因素的比较 杜飞，张李，陈代刚，杨华军 遵义市第一人民医院呼吸内科（贵州遵义  563000 ） 【摘要】   目的    研究不同程度的慢性阻塞性肺疾病（简称慢阻肺）患者合并心血管疾病及其危险因素的患 病率。方法    选取 2014 年 1 月至 2016 年 1 月我科收治的 50 例轻至中度和 50 例重度到极重度慢阻肺患者。从病 历资料和临床评估合并症情况，同时计算 Charlson 合并症指数和医院焦虑抑郁量表（HADS ）评分。结果    与重度 极重度慢阻肺患者比较，轻度至中度慢阻肺患者中吸烟、抑郁和血脂异常的患病率更高（P均0.001）。两组患者 合并高血压、糖尿病、酒精中毒和慢性心力衰竭比较常见，而两组 Charlson 合并症指数和 HADS 评分无显著差 异。结论    慢阻肺无论其严重程度，合并症发生率均很高。某些心血管疾病的危险因素，如吸烟、血脂异常和抑 郁，在轻中度慢阻肺的患者中更为普遍。 【关键词】  慢性阻塞性肺疾病；心血管疾病；危险因素 Comparison of cardiovascular risk factors in patients with chronic obstructive pulmonary disease with different severities DU Fei, ZHANG Li, CHEN Daigang, YANG Huajun Department of Respiratory Medicine, The First People’s Hospital of Zunyi, Institute of Respiratory Diseases, Zunyi, GuiZhou 563000, P.R.China Corresponding author: DU Fei, Email: fei632@163.com 【Abstract 】 Objectives    To analyze the risk factors for cardiovascular disease (CVD) in patients with chronic obstructive pulmonary disease (COPD) in different severity. Methods    The study included 50 patients with mild-to- moderate COPD and 50 with severe-to-very severe COPD admitted between January 2014 and January 2016. Comorbidities were recorded on the basis of data obtained from medical charts and clinical evaluations. The Charlson comorbidity index was calculated, and the Hospital Anxiety and Depression Scale (HADS) score was determined in each subjects. Results    There were more prevalences of smoking, depression and dyslipidemia in the patients with mild-to- moderate COPD than those with severe-to-very severe COPD (all P 0.001). The prevalences of high blood pressure, diabete