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甘露醇应用误区及经验(Mistakes and experiences in mannitol application)
甘露醇应用误区及经验(Mistakes and experiences in mannitol application)
Sensitized tablet
Sensitive make Lang piece (Betahistine Mesilate Tablets) commodity name: sensitive make Lang
Function and effect:
The following diseases are accompanied by dizziness and dizziness.
Meyniers disease, Meyniers syndrome, vertigo.
pharmacological action
1. improvement of internal circulation disorders
In the experiment of the circulatory disorder in the inner ear of rats, intraperitoneal administration of this agent, 30 minutes later, increased the blood flow by 148% compared with the control group. This phenomenon is a specific phenomenon observed in pathological conditions.
2. elimination of endolymphatic hydrops
In anesthetized dogs, the lymphatic flow rate of the disposable chest tube was increased by 2-35 times after intravenous injection of the agent. This is considered to be the discharge of the edematous fluid.
In addition, the dynamic observation of the inner ear blood flow of the rats showed that the static pressure of the inner ear decreased and the amplitude of the pulse increased. By throwing in with this agent, the inner ear blood flow is increased, while the secretion and absorption of the inner ear fluid are promoted.
3. improvement of blood flow in the brain
The experiments on anesthetized dogs showed that the blood flow of the internal carotid artery was increased by more than 50% after intravenous administration. This effect is not antagonized by the pretreatment of the antihistamine, but tends to increase.
clinical application
1. clinical efficacy
A total of 875 clinical trials including a double-blind trial showed that the agent was effective against dizziness, dizziness, Meyniers disease, Meyniers syndrome, vertigo, and so on.
The incidence of 2. side effects and its impact on clinical trial values
Of the total 2254 cases, 26 were reported (1.2%), and the main side effects were nausea (10) (0.4%),
A rash of 3 people (0.1%).
In addition, there was no significant change in
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