中药对家兔实验性膝关节骨性关节炎氧自由基代谢的影响(Effect of Chinese herbal medicine on oxygen free radical metabolism in experimental knee osteoarthritis in rabbits).docVIP
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中药对家兔实验性膝关节骨性关节炎氧自由基代谢的影响(Effect of Chinese herbal medicine on oxygen free radical metabolism in experimental knee osteoarthritis in rabbits)
中药对家兔实验性膝关节骨性关节炎氧自由基代谢的影响(Effect of Chinese herbal medicine on oxygen free radical metabolism in experimental knee osteoarthritis in rabbits)
Effect of Chinese herbal medicine on oxygen free radical metabolism in experimental knee osteoarthritis in rabbits
Update Date: 2009-07-03 click:
Ma Jianbing, Liu Deyu, Li Kanyin, Sha Hao ferry, Meng Xiangdong
Abstract Objective: To study the effect of Chinese medicine on oxygen free radical metabolism in osteoarthritis, the replicated in rabbit models of knee osteoarthritis were randomly divided into model group, Fenbid group and Chinese medicine Zhubi Decoction group Hulth method. The activity of superoxide dismutase (SOD) and the content of serum lipid peroxide (LPO) in erythrocytes were measured after 1 months, and statistically analyzed. The results showed that Zhubi Decoction group animal SOD activity was significantly higher than the other two groups, while the content of LPO was significantly lower than that of the other two groups (P 0.01), the model group and Fenbid group had no significant difference (P 0.05). It is concluded that the decoction of eliminating arthralgia can significantly increase the activity of SOD and reduce the content of LPO, thus delaying the degeneration of articular cartilage and promoting the cartilage repair.
Keywords knee osteoarthritis / oxygen free radical metabolism / drug effects of Chinese medicine animal experimental study in rabbits
CLC number: R289.5; R648.3 document identifier: A
Article number: 1001-6015 (2000) -0008-02
THE, INFLUENCE, OF, TRADITIONAL, CHINESE, ON, THE, METABOLISM, OF, OXYGEN, FREE, DRUGS, RADICAL, IN,, EXPERIMENTAL, RABBIT, KNEE, OSTEOARTHRITIS
Ma, Jianbing, Liu, Deyu, Li, Kanyin
(Red-Cross-Society, Hospital, of, Xi-an, City, Shaanxi, Province, Xi-an, 710054)
In order to explore the influence of traditional Chinese drugs (TCD) on the metabolism of oxygen free radical in osteoarthritis, rabbit models of knee osteoarthritis were made by Hulth s method and random
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