骨母细胞生长于生物活性微弧氧化层之界面研究interfacial - yoke.pdfVIP

骨母細胞生長於生物活性微弧氧化層之界面研究 Interfacial Study of the Osteoblast Growth on Micro-arc Oxidized Bioactive Layers 1 *,1 2 3 1 楊睬晴 舒惠瑛 陳賢德 鍾啟仁 何主亮 1 *,1 2 3 1 Tsai-Ching Yang Hui-Ying Shu Hsien-Te Chen Chi-Jen Chung Ju-Liang He 1 2 逢甲大學材料科學與工程學系 中國醫藥大學附設醫院骨科部 3 中臺科技大學牙體技術暨材料系 1Department of Materials Science and Engineering, Feng Chia University, No. 100, Wenhwa Rd., Seatwen District, Taichung City 40724, Taiwan. 2Department of Orthopaedic Surgery, China Medical University Hospital, No. 2 Yuh - Der Rd., North District, Taichung City 40447, Taiwan. 3Department of Dental Technology and Materials Science, Central Taiwan University of Science and Technology, No. 666, Buzih Rd., Beitun District, Taichung City 40601 Taiwan. 摘要 Abstract 利用微弧氧化技術(micro-arc oxidation, The oxide layer of titanium which MAO)在鈦金屬表面生成多種氧化層，皆已被 generated by micro-arc oxidation (MAO) has 驗證俱有生物活性，從而提升骨整合 been verified with excellent cell compatibility and osseointegration. However, the studies (Osseointegration)能力。然而現今研究對於鍍 about biological character of TiO2 coatings are 層之細胞相容性評估大多僅止於細胞活性分 mostly focus on in vitro cell activity analysis, 析 。本研究擬針對微弧氧化所生成之銳鈦礦 This study will disclose how the anatase 二氧化鈦(A-TiO ) 、金紅石二氧化鈦 (A-TiO ), rutile (R-TiO ), hydroxyapatite 2