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基因功能研究方法进展重点讲义
现有的TALEN、ZFN及CRISPR相关设计数据库资源 工程修饰的核酸酶在人类遗传病治疗中的研究 Thomas Gaj, Charles A. Gersbach, and Carlos F. Barbas III. (2013) ZFN, TALEN, and CRISPR/Cas- based methods for genome engineering. Trends in Biotechnology, 31(7): 397-405. 2. Yongsub Kim, Jiyeon Kweon, Annie Kim, Jae Kyung Chon, Ji Yeon Yoo, Hye Joo Kim, Sojung Kim, Choongil Lee, et al. (2013). A library of TAL effector nucleases spanning the human genome. Nature Biotechnology, 31(3): 233-239. 3. Yongsub Kim, Jiyeon Kweon, Annie Kim, Jae Kyung Chon, Ji Yeon Yoo, Hye Joo Kim1, Sojung Kim, et al. (2013) A library of TAL effector nucleases spanning the human genome. Nature Biotechnology, 31(3): 251-260. 4. Chuanxian Wei, Jiyong Liu, Zhongsheng Yu, Bo Zhang, Guanjun Gao, Renjie Jiao. (2013) TALEN or Cas9 e Rapid, Efficient and Specific Choices for Genome Modifications. Journal of Genetics and Genomics, 40(1): 281-289. 5. Qiurong Ding, Youn-Kyoung Lee, Esperance A.K. Schaefer, Derek T. Peters1, Adrian Veres, Kevin Kim, Nicolas Kuperwasser, et al. (2012) A TALEN genome-editing system for generating human stem cell-based disease models. Cell Stem Cell, 12(2): 238–251. 参考文献 6. Victoria M. Bedell, Ying Wang, Jarryd M. Campbell, Tanya L. Poshusta, Colby G. Starker, Randall G. Krug II, et al. (2012) In vivo genome editing using a high-efficiency TALEN system. Nature, 491(7422): 114-118. 7. Yang J, Zhang Y, Yuan P, et al. Complete decoding of TAL effectors for DNA recognition. Cell research, 2014, in press. 8. Dana Carroll. (2011) Genome engineering with zinc-finger nucleases. Genetics, 188(4): 773-82. 9. Dana Carroll. (2008) Zinc-finger Nucleases as Gene Therapy Agents. Gene Therapy, 15(22): 1463–1468. 10. Palpant NJ, Dudzinski D. (2013) Zinc finger nucleases: looking toward translation. Gene Therapy, 20(2):121-7. 参考文献 11. Severine Remy, Laurent Tesson, Severine Menoret, Claire Usal, Andrew M. Scharenberg, Ignacio Anegon. (2010) Zinc-finger nucleases: a powerful tool for genetic engineering of animals. Transgenic Resea
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