青岛市孕妇碘营养状况分析及其对母体甲状腺功能和新生儿碘营养状况的影响.pdfVIP

对孕妇甲状腺功能和新生儿TSH水平造成明显影响,但应重视对孕妇尿碘水平的监测, 并加强相关知识的宣传教育，指导孕妇科学补碘，防患于未然。 硕士研究生 于春华（营养与食品卫生学） 指导教师 梁惠 教授 关键词: 孕妇; 新生儿; 碘营养; 甲状腺功能 万方数据 Abstract Objective The aim of this study was to investigate the pregnant women’s level of iodine nutrition and its influence factors in Qingdao, and to analyze the influence of the different iodine nutritional status on the pregnant women’s thyroid hormone levels, the neonatal iodine nutritional status and the levels of TSH. Method We detected the iodine content in 600 urine samples of the pregnant women who were treated in Qingdao women and children hospital and the Qingdao peoples hospital from April to October 2013, and designed questionnaire to understand their iodine intake conditions and the knowledge of iodine nutrition. Then 198 third trimester pregnant women were randomly selected (28th week of gestation or greater) .We used ammonium persulfate digestible – arsenic-cerium catalyzed spectrophotometry to determine the urine iodine level, and chemiluminescence to measure the levels of the three iodine determination of serum free thyroid glycine (FT ), free thyroxine (FT ) and 3 4 thyroid-stimulating hormone (TSH) in their venous blood. The urine iodine from the normal full-term newborns within 48 hours was detected, and also the TSH level of heel blood from the normal full-term newborns within 72 hours was measured by the chemiluminescence analysis method. Result The urine iodine median of the 600 urine specimens was 1