恶性黑色素瘤31页课件2.pptVIP

catalogue What is malignant melanoma? Melanoma triggers and causes Primary sites Clinical characteristics Early clinical performance Late-stage clinical manifestations Pathological type Treatment 2010 melanoma field progress review What is malignant melanoma? Malignant melanoma, also known as melanoma, is the origin of epidermal melanocyte or nevus of malignant tumors.?The disease can be seen at any age, more seen in middle-aged and older, women slightly more than men. Melanoma triggers and causes Air pollution To pursue beauty The lack of medicine knowledge Immune deficiency Abusing the estrogen drugs Malignant transformation of black mole Racial genetic factors Trauma and chronic stimulation factors Air pollution Harmful ultraviolet light and some harmful material in the air make a difference of human skin, causing melanocyte abnormal expression, trigger melanoma.  To pursue beauty Racial genetic factors Malignant melanoma occur in the white race. For the incidence of world each year to less than 1 ~ 2/10 million, but Australias Queensland annual incidence of 16/10 million population, it is the world‘s leading high incidence of malignant melanoma. Africa and Asian people rarely have the sickness. Primary sites Malignant melanoma 90 % occurs in the skin, the most common in the back, metal-studded ,leg, foot, toe, nail bed, scalp and so on ; a few occurs in vulvae, digestive tract and eyes. Eye lesions?and Oral lesions ◆ Generally speaking moles surface is smooth, melanoma of surface is coarser. If the surface is smooth, and suddenly becomes coarse or , we should pay attention to it. ◆Ulceration not only is one of the important melanoma clinical manifestations which is different from mole, but also has the meaning of prognosis than no ulcer. ◆Patients of malignant melanoma generally are the old; the youth or children melanoma are rare . Early clinical performance Color: a mole increase in size, pigment or darker or lighter, a mole deepen, shi