微波促进碱性离子液体催化合成查尔酮.pdfVIP

学兔兔 2015年第23卷 合成化学 Vo1．23，2015 第3期，202—205 Chinese Journal of Synthetic Chemistry No．3，202—205 · 研究论文· 微波促进碱性离子液体催化合成查尔酮 王壮坤 (辽宁石化职业技术学院石油化工系，辽宁锦州 121001) 摘要：以4-氯．1一丁醇，Ⅳ-甲基咪唑和苯甲酸钠为原料，用微波法制得碱性离子液体{[OHBMIM]PhCOO (Am)}，其结构经F-r—IR表征；以苯甲醛和苯乙酮为原料，AIL为催化剂，经微波促进的缩合反应合成了查尔 酮(1)，其结构经 H NMR和FT-IR确证。考察了A】 用量、微波功率、物料比和反应时间对1产率的影响。合 成1的最佳反应条件为：AlL 1 mmol，苯甲醛5 mmol，n(苯甲醛)：，l(苯乙酮)=1．1，于微波功率140 W反应 5 min，产率95．8％。AIL具有较好的循环使用性，循环使用6次，1产率没有明显降低。 关 键 词：碱性离子液体；微波促进；查尔酮；合成；工艺优化 中图分类号：O621．3；0625．31 文献标识码：A DOI：10．15952／j．cnki．cj sc．1005—1511．2015．03．0202 Alkaline Ionic Liquid Catalytical Synthesis of Chalcone Under Microwave Irradiation WANG Zhuang—kun (Department of Petrochemical，Liaoning Petroechemical Vocational And Technology，Jinzhou 121001，China) Abstract：Alkaline ionic liquid{[OHBMIM]PhCO0(AIL)}was prepared via microwave method， using 4-chloro-1一butanol，N-methyl—imidazole and sodium benzoate as the materials．The stmcture was confirmed by FI一IR．Chalcone(1)was synthesized by microwave irradiated condensation reaction of benzaldehyde with acetophenone．The structure was confirmed by H NMR and FT—IR．The effects of Al1．dosage，microwave power，materials ratio and reaction time on the yield of 1 were investiga— ted．Th e optimum reaction conditions of 1 at 140 W for 5 min were as follows：AIL was 1 mmol， benzaldehyde was 5 mmol，n(benzaldehyde)：n(acetophenone)was 1．1．The yield of 1 was 95．8％ under the optimum reaction conditions．AIL exhibits good cycle performance that