56例腺样体肥大患儿血清 14 种食物原特异性 IgG抗体检测-20100218.pdfVIP

56 例腺样体肥大患儿血清14 种食物过敏原 特异性IgG 抗体的检测 伊力哈木.依马木，张华* 摘要: 目的: 通过对腺样体肥大患儿进行食物不耐受检测,了解腺样体肥大 患儿食物过敏情况。方法: 选取新疆医科大学第一附属耳鼻咽喉科2008 年 4 月 - 2009 年 12 月收住的腺样体肥大患儿56 例。男36 例,女20 例;年龄5.3 (1～ 12)岁。抽取腺样体肥大患儿静脉血 2 mL,分离血清,采用酶联免疫法按试剂盒说 明书检测患儿血清 14 种食物变应原 IgG 水平。结果: 56 例腺样体肥大患儿进 行食物不耐受检测,其中53 例结果阳性,阳性率达94.64%。,食物特异性 IgG 升 高以鸡蛋94.64%最高,其次是牛奶91.07% 及鳕鱼26.79%。结论：食物不耐受可 能是腺样体肥大患儿的潜在病因之一，因此食物过敏原检测可以作为临床治疗的 参考之一,并可指导腺样体肥大患儿的饮食。 关键词: 特异性 IgG 抗体; 食物过敏原; 腺样体肥大; 过敏性疾病 Analysis of Food Intolerance Test in Children with adenoids hypertrophy Abstract: Objective To understand the information of food hypersensitivity of children with adenoids hypertrophy by food intolerance test . Methods : 56 children (36 boys and 20 girls ; aged from 1 t o 12) with adenoids hypertrophy who were hospitalized in our hospital from Aprel.2008 to December.2009 were chosen . Two mils venous blood was collected from each object, separated serum. Enzymelinked immunos orbent assay method was applied to detect the serum concentration of 14 kinds food allergen IgG in 56 children with adenoids hypertrophy . Results :The positive rate was 94.64% in 56 caseswith adenoids hypertrophy. The positive rates of 14 food allergen IgG were as follow: egg 94.64% ,milk 91.07% , ling 26.79%. Conclusion：Food intolerance maybe one cause of adenoids hypertrophy in children ,so food intolerance test is a useful method for children with adenoids hypertrophy to find food allergen and guideline for diet of these children . 腺样体肥大是引起儿童鼻阻塞 、鼻窦炎 、儿童睡眠呼吸暂停低通气综合 征 、卡他性中耳炎的常见病因之一 ,严重的可致儿童颌面部、胸部发育畸形 、 心肺功能损伤等。临床上常见的治疗方法是经口腺样体切除术。 目前公认儿童睡眠呼吸暂停低通气综合征(POSAHS)的首要病因为腺样体和 【1】 腭扁桃体肥大 腺样体肥大不仅造成咽鼓管机械性阻塞、咽鼓管逆流 ,还可作 为致病菌的“ 储蓄池 ” 和局部免疫异常的始动因素。腺样体肥大亦是诱发儿 童分泌性中耳炎的重要因素之一。最近研究表明 OME 与变态反应有关, 且以 I 【2】 【3】【4】 型变态反应为多见 , 其中嗜酸性粒细胞是主要炎性细胞