子宫压缩乏力惹起产后出血的防备和治疗(国外英文资料).docVIP

子宫收缩乏力引起产后出血的预防和治疗 Hangzhou guangren hospital The contractions of the uterus causes the prevention and treatment of postpartum hemorrhage Postpartum hemorrhage is a serious complications during delivery. According to the 1983-1984 the country 24 provinces and cities in 6241 cases of maternal blood loss measurement results put forward the definition of postpartum hemorrhage is from birth to 2 hours after fetal childbirth haemorrhage amount = 400 ml or to fetal childbirth within 24 hours after the bleeding = 500 ml [1]. The main causes of postpartum hemorrhage were uterine contractions fatigue; Soft birth canal injury; The placenta factors; This paper deals with the prevention and treatment of postpartum hemorrhage due to the weak contractions of the uterus. The mechanism of postpartum hemorrhage Postpartum haemorrhage is uterine muscle fiber structure features and joint decision mechanism of blood clotting. Uterine contractions of the impetus from the endogenous release of oxytocin and prostaglandin. Intracellular ca2 + ions is muscle excited - contraction coupling of activator, oxytocin release and promote calcium ions to flow into the muscle cells, and prostaglandins is calcium ionophore, and calcium ions form complex, carry calcium ions into the cell. Into the muscle cells of calcium ion and actin, muscle knots and cause uterine contractions of plasma protein and complex, the oppression hemostasis effect to the walls of blood vessels. At the same time due to muscle contraction after vascular twists and turns, blocking blood flow, promotes thrombosis, blood sinus closed. But still can relax after the muscle fibers of the uterus to contract, thus the oppressed vessels can be exposed to open and continue bleeding again, the basic mechanism of hemostasis is blood clotting. Blood during pregnancy in high coagulation state, under the effect of endogenous prostaglandins, a large number of platelet aggregation, the aggregation of platelet release of vascular active sub