原发性震颤与帕金森氏(国外英文资料).docVIP

原发性震颤与帕金森氏 Parkinsons disease Parkinsons syndrome (parkinosonism), also known as Parkinsons disease (paralgsisagitans) is a kind of slow nervous system degenerative disease of the brain a striate nigra system of pigment neurons dopamine neurons degenerative diseases, result in the substantia nigra striatum dopamine neurotransmission material generation and utilization ratio, causing the central nervous system extrapyramidal chronic sexual dysfunction. Good hair age 50 ~ 80 years old. First, etiology and pathogenesis The etiology is unknown, and there are a few possible causes: (1) by taking large doses of sedatives and antipsychotics, these drugs block dopamine receptors and dopamine, which causes dopamine Unable to exert inhibiting effect, the drug depletes the brain of dopamine, which depletes dopamine. (2) the multiple cerebral infarction, encephalitis, and basal calcification of the basal ganglia decreased the dopamine synthesis. (3) poisoning of carbon monoxide, mercury and manganese. (4) folic acid deficiency can increase susceptibility to Parkinsons disease. Folate deficiency increases homocysteine in the body and increases the damage to black cells. Animal studies have shown that the use of folic acid to repair dark matter can also combat the toxic effects of cysteine. The common pathologic basis is the damage of the dopamine system in the basal ganglia, and the inhibition of dopamine decreases, causing dyskinesia. The main manifestations are tremor, muscular rigidity, decrease in motion, unstable gait, starting and stopping difficulty, lead tube sample movement, and masked face. Prone to fracture and long bed, susceptible to infection. In severe cases, dystrophy and malnutrition occur. Infection often kills people. The problem of nutrition The causes of Parkinsons disease are mainly due to the following aspects: (1) eating is difficult. When the disease is getting worse, the body is rigid and the ability to live is reduced, including meals. The head and ne