儿童血液及造血系统疾病(国外英文资料).docVIP

儿童血液及造血系统疾病 Chapter vi disease of blood and hematopoietic system Nutritional deficiency anemia Diagnostic point Iron deficiency anemia is caused by a lack of from food intake of iron, and the decrease of the storage of iron in the body, reduce cellule low pigment anemia caused by hemoglobin, see more at 6 months to 2 years old baby, is one of the key of the prevention and control of disease in our country. One, clinical manifestation Poor feeding and untimely addition of iron-rich food history. The skin mucosa is fading, fatigue and inactivity. 3, can have digestive function disorder, appetite is abate, picorophagy. Memory loss, concentration, and anemia, heart rate increase, heart enlargement. Its easy to get infected. Second, auxiliary inspection 1, small cell hypochromic anemia, hemoglobin 10-3 months 100g/L; 3 months - 6 years old 110g/L; 6-14 120 g/L; Red blood cell morphology is shown to be significantly lower in pigment: MCV 80fL, MCHC 0.31, MCH 26pg, blood smear with small cells, light color, and enlarged central area. 2, serum iron 10.7 umol/L ( 60ug/dL), total iron binding force: 62.7 mu/L; Ferroprotein saturation 15% is referenced, 10% has definite meaning. 3, bone marrow iron granule cells 15%, red blood cells are significantly reduced and disappeared. 4, the red blood cell free porphyrin 500 mu g/L. Serum iron protein 16ug/L. Iron treatment is effective. The treatment principle: Identify and remove the cause of the disease: take care to avoid infection. Food therapy should improve the diet, increase the intake of rich iron and vitamin C. 3, drug treatment General oral iron therapy: iron 4-6 mg/kg. D, with ferrous sulfate 20-30 mg/day (enough to increase the blood protein 0.4 g/dL/d), at the same time of oral vitamin C50-200 mg/day, to the normal hemoglobin maintenance treatment after 1-3 months. Treatment response: the net wetting erythrocyte increases from 2 to 4 days after treatment, 7 to 10 days peak, 2 to 3 weeks to normal. Hemoglobin