血栓抽吸对急性心肌梗死预后的影响.docx

血栓抽吸对急性心肌梗死预后的影响 【摘要】目的：研究急性心肌梗死应用血栓抽吸导管辅助治疗对临床预后的影响。方法：选取我院心血管病科于2014年1月~2015年6月拟行经皮冠状动脉介入治疗（Percutaneous coronary intervention，PCI）的急性ST段抬高型心肌梗死（ST-segment elevation myocardial infarction，STEMI）患者72例，以单盲计算机随机法分为观察组（血栓抽吸联合PCI，36例）和对照组（直接PCI，36例），对比两组术中无复流发生率、术后心脏超声指标变化及MACE发生率。结果：观察组无复流发生率（13.89%），显著低于对照组（44.44%），P0.05；术后1周、6个月及12个月时，观察组的左心射血分数（left ventricular ejection fraction ，LVEF）均显著高于对照组（P0.05）；观察组左心室舒张末期内径（left ventricular end-diastolic dimension ，LVEDD）、左心室收缩末期内径（left ventricular end-systolic dimension，LVESD）显著低于对照组，P0.05；术后1个月，观察组的主要心血管不良事件（major adverse cardiovascular events，MACE）发生率（5.56%）显著低于对照组（16.67%），P0.05。结论：血栓抽吸导管应用于STEMI患者的PCI治疗能够降低无复流发生率及MACE发生率，改善心脏功能参数，临床预后优于直接PCI治疗。 【关键词】急性心肌梗死；经皮冠状动脉介入治疗；血栓抽吸；临床预后 The influence of thrombus aspiration on the prognosis of acute myocardial infarction 【 abstract 】 objective: to study the acute myocardial infarction, thrombus suction catheter adjuvant treatment effect on clinical outcomes. Methods: to choose our cardiovascular disease department in from January 2014 to June 2015 to suffer coronary interention (Percutaneous coronary intervention, PCI) for the treatment of acute ST segment elevation myocardial infarction (ST - segment elevation myocardial infarction, STEMI), 72 cases of patients, with computer random single blind method, divided into observation group (thrombus suction joint PCI, 36 cases) and control group (direct PCI, 36 cases) and compare the intraoperative retention rate, the two groups postoperative cardiac ultrasound index change and incidence of MACE. Results: the observation group no reflow rate (13.89%), significantly lower than that of control group (44.44%), P 0.05; After 1 week, 6 months and 12 months, the observation group of left heart ejection fraction, left ventricular ejection fraction, LVEF) were significantly higher than that of control group (P 0.05); Left ventricular end-diastolic diameter, left ventricular end - diastolic dimension, LVEDD), left ventricular end systolic diam