Cutoff score and responsiveness of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8) in a Large daily disposable contact lens registry.pdfVIP

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Cutoff score and responsiveness of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8) in a Large daily disposable contact lens registry.pdf

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Cutoff score and responsiveness of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8) in a Large daily disposable contact lens registry.pdf

Contact Lens and Anterior Eye 39 (2016) 342–352 Contents lists available at ScienceDirect Contact Lens and Anterior Eye journal homepage: /locate/clae Cutoff score and responsiveness of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8) in a Large daily disposable contact lens registry Robin L. Chalmers*, Lisa Keay, Sheila B. Hickson-Curran, William J. Gleason 2097 East Lake Rd., Atlanta, GA 30307, United States ARTICLE INFO Article history: Received 29 December 2015 Received in revised form 11 April 2016 Accepted 18 April 2016 Keywords: Contact lens symptoms CLDEQ-8 Daily disposable Questionnaires Clinically important difference ABSTRACT Purpose: To report (1) results of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8) among a large sample of SCL wearers before and during 1 year after ?tting with one of 2 daily disposable (DD) lenses (eta?lcon A or nara?lcon B) in the TEMPO Registry, (2) the cut-off score to identify highly symptomatic SCL wearers and (3) the clinically important difference (CID) in the CLDEQ-8 score. Methods: Demographics, CL history and patterns of SCL use were documented. Construct validity of the CLDEQ-8 was tested versus overall opinion (OO) of habitual SCLs, eye dryness and eye sensitivity at baseline. Responsiveness to change in OO was tested. Cutoff score, CID, and predictive accuracy were analyzed with general linear mixed models, adjusting for clustering by site with Bonferoni correction for multiple comparisons. Results: Baseline CLDEQ-8 data from 977 habitual SCL wearers showed signi?cant association with OO, eye dryness and sensitivity (p0.0001, all). CLDEQ-8 scores improved signi?cantly after re?tting and re?ected change in OO over time (p0.0001). Diagnostic cutoff of ! 12 and CID of 3 points performed best. Conclusions: The CLDEQ-8 score of !12 points is proposed to identify SCL wearers who could bene?t from clinical management of their CL-related symptoms. The clinically important difference was ?3 points. Re?tting to th