放大胃镜诊断早期胃癌及癌前病变的临床价值.docVIP

放大胃镜诊断早期胃癌及癌前病变的临床价值 　　【摘要】 目的：通过比较放大胃镜和普通胃镜对胃癌及癌前病变的检出率，评价放大胃镜对早期胃癌及癌前病变定性诊断的临床价值。方法：选取本院2014年1月-2015年2月申请胃镜检查的286例患者作为研究对象。143例行放大胃镜检查患者作为放大胃镜组，观察其胃小凹形态，指导靶向活检，标本送病理检查；143例行普通胃镜检查患者作为普通胃镜组，对其进行常规黏膜活检，标本送病理检查。结果：两组早期胃癌及癌前病变检出结果比较，差异有统计学意义（P0.05）；不同胃小凹分型Hp感染情况比较，差异无统计学意义（P0.05）。结论：放大胃镜对早期胃癌及癌前病变的诊断价值优于普通胃镜，应用放大胃镜有助于发现早期胃癌及癌前病变。 　　【关键词】 放大胃镜； 普通胃镜； 早期胃癌； 癌前病变 　　【Abstract】 Objective：To evaluate the clinical value of magnification endoscopy for the diagnosis of early gastric carcinoma and precancerous lesions by comparing the detection rates of gastric cancer and precancerous lesions between amplification gastroscope and ordinary gastroscope.Method：286 patients who applied for gastroscopy in our hospital from January 2014 to February 2015 were selected as the research objects.143 patients who were detected with magnification endoscopy were selected as the magnification endoscopy group，their gastric pits form was observed，target biopsy was given to them，their specimens were sent for pathologic examination.143 patients who underwent ordinary gastroscope were selected as the ordinary gastroscope group，normal mucosa biopsy was given to them，their specimens were sent for pathologic examination.Result：The differences were statistically significant in the overall detection rate of early gastric carcinoma and precancerous lesions between the two groups（P0.05）.The difference in Hp infection of different gastric pit types was not statistically significant（P0.05）.Conclusion：Magnification endoscopy is superior to general endoscopy in the diagnosis of early gastric carcinoma and precancerous lesions.Magnification endoscopy is helpful to the diagnosis of early gastric cancer and precancerous lesions. 　　【Key words】 Magnification endoscopy； General endoscopy； Early gastric cancer； Precancerous lesions 　　First-author’s address：The Fourth People’s Hospital of Tongling City，Tongling 244000，China 　　doi：10.3969/j.issn.1674-4985.2016.02.007 　　胃癌是我国最常见的恶性肿瘤之一，其发病率及死亡率均居恶性肿瘤的前三位，治疗