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How to differentiate function and non-function interstitial fluids Function:Taking part in modulating the balance of body fluids. How to differentiate function and non-function interstitial fluids Non-function: Fluids in cavity in normal status.Including cerebrospinal ,joint,pericardium and abdominal cavity fluids Third Space Definition: Pathophysiologiclly, relatively nonfunctional extra cellular fluid.Mainly for the change of quantity of functional and nonfunctional ECF. Third Space Distribution: exudates in burns; ascites; soft tissue injuries. bowel wall;peritoneum;infected lesions. Attention: not confused with the nonfunctioning components from interstitial fluid. Pressure leading to the shift of water through semi-permeable membrane Definition the number of osmotically active particles or ions per unit volume. Unit : milliosmoles per liter (mOsm / L) Relation between Osmotic pressure and distribution of body fluid Osmotic Pressure: Crystal OP and Colloid OP Plasma Crystal OP : [Na+] contributes to a major portion of OP Relation between Osmotic pressure and distribution of body fluid Plasmatic Colloid OP: Plasma protein contributes a force leading to distribution of ECF Interstitial Crystal OP: Contributes to the shift of extracellular and intracellular water The Regulation of Body Fluid Balance Maintaining normal osmotic pressure Maintaining normal concentration Integral dose of natrium Maintaining normal Volume (Blood-volume) The Regulation of Body Fluid Balance Maintaining osmotic pressure The Regulation of Body Fluid Balance Maintaining the concentration Integral dose of natrium The Regulation of Body Fluid Balance Volume regulation(Blood-volume) Classification of body fluid change( Four Types ) Volume Changes(ECF) Volume Deficit Volume Excess Concentration Changes Hyponatremia Hypernatremia Classification of body fluid change( Four Types ) Mixed volu
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