表阿霉素所致外周静脉反应的预防措施探讨.docVIP

表阿霉素致外周静脉反应的综合防治探讨 杨娟 郧阳医学院护理学院附属东风总医院乳腺外科 湖北十堰 442008 摘要：目的：探讨表阿霉素致外周静脉反应的防治方法，以减轻病人痛苦，使整个化疗周期顺利完成。方法：将接受表阿霉素化疗的98例病人随机分为对照组与观察组各49例，对照组实施常规化疗护理，观察组在此基础上改用避光输液器与深色布套遮盖药液，采用静脉留置针（16号）穿刺置管，穿刺处湿敷25%硫酸镁与2%利多卡因混合液纱布，并建立一套静脉使用计划。比较两组静脉反应发生率及药液渗漏情况。结果：观察组静脉反应发生率及药液渗漏率显著低于对照组（P 0.05），整个化疗周期结束，观察组血管评估显著优于对照组（P0.01）。结论：药液颜色的遮盖、静脉留置针的使用、化疗同步25%硫酸镁与2%利多卡因的湿敷及完善的静脉使用计划可有效预防静脉反应的发生，并减轻表阿霉素对血管的损伤。 关键词：表阿霉素； 静脉反应； 综合防治 Prophylaxis and Treatment of Phlebitis Caused by Pharmorubicin//YANG juan//(Depar- tment of Galactophore Surgery,Dong Feng General Hospital affiliated to College of Nursing of Yun Yang Medical School,Hubei 442008,China) Abstract:Objective To explore methods for preventing and curing phlebitis caused by pharmorubicin. Methods 98 patients undergoing chemotherapy with pharmorubicin were randomly divided into a control group and an observation group equally. Patients in the control group were given conventional nursing care, while those in the observation group were subjected to external application of lucifugal infusion apparatus and drug, Venous Retention Needls, hydropathic compress with the miscible liquids of 25 percent magnesium sulfate and 2 percent lidocaine ,and systematic transfusion on the basis of the conventional nursing care.The incidence rate of phlebitis was compared. Result The incidence rate of phlebitis in the observation group was significantly less than that in the control group(p0.01).The status of vein in the observation group was significantly better than that in the control group(p0.01).conclusion Lucifugal drug, applications of Venous Retention Needls, hydropathic compress with the miscible liquids of 25 percent magnesium sulfate and 2 percent lidocaine ,and systematic transfusion can prevent phlebitis effectively and relieve the pharmorubicin-induced trauma of vein. Key words: pharmorubicin ；phlebitis ；prophylaxis and treatment 表阿霉素（EADM）是一种抑制核酸合成与有丝分裂的抗癌新药物，对中晚期乳腺癌及小细胞肺癌疗效显著，心脏毒副作用明显低于阿霉素，已广泛应用于临床。EADM为鲜红色或橙红色冻干块状物，有引湿性，外周静脉滴入给病人造成极大的