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East Texas Medical Center – TylerAnnual Physician EducationMDRO-Multidrug-Resistant Organisms-Revised: April 2013 Preventing Multidrug-Resistant Organisms (MDROs) What the Direct Caregiver Should Know Objectives:Upon completion of this module, the learner will : Define Multidrug Resistant Organisms (MDRO) Name 2 MDROs State the type of precautions to be used with all patients and under what circumstances you would wear gloves Name the type of isolation in which to place someone with an MDRO What are Multi-Drug Resistant Organisms? (MDROs) MDROs are microorganisms, predominantly bacteria, that are resistant to one or more classes of antimicrobial agents Examples of MDROs (not all inclusive) are: Methicillin-resistant staphylococcus aureus (MRSA) Vancomycin-intermediate staphylococcus aureus (VISA) Vancomycin-resistant staphylococus aureus (VRSA) Vancomycin-resistant enterococcus (VRE) Streptococcus pneumoniae resistant to penicillin and other broad-spectrum agents Acinetobacter baumannii Carbapenem-resistant Enterobacteriaceae (CRE) What are Multi-Drug Resistant Organisms? (MDROs) Other Examples of MDROs are: Some gram-negative organisms with strains that have developed the ability to produce ESBL (extended-spectrum beta-lactamase) which is an enzyme that inactivates beta-lactam antibiotics such as the penicillins and cephalasporins Klebsiella pneumonia Escherichia coli (E. Coli) Acinetobacter baumannii Stenotrophomonas maltophilia Why Concern over MDRO Infections? MDROs cause serious, difficult-to-treat infections that can result in substantial morbidity, mortality, increased lengths of stay and excess cost. Frequently preventable – Usually acquired via transmission by: caregiver-to-patient, environment-to-patient, or patient-to-patient. Judicious use of antimicrobials may decrease incidence of microorganisms developing antibiotic resistance. What Measures Can We Take to Prevent Transmission of
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