离子移动质谱.docx

From Wikipedia, the free encyclopediaAn ion mobility spectrometer separates ions by shape and charge.Ion-mobility spectrometry?(IMS) is an analytical technique used to separate and identify ionized molecules in the gas phase based on their mobility in a carrier buffer gas. Though heavily employed for military or security purposes, such as detecting drugs and explosives, the technique also has many laboratory analytical applications, recently being coupled with?/wiki/Mass_spectrometrymass spectrometry?and?/wiki/High-performance_liquid_chromatographyhigh-performance liquid chromatography. IMS devices come in a wide range of sizes (often tailored for a specific application) and are capable of operating under a broad range of conditions. Systems operated at higher pressure (i.e. atmospheric conditions, 1 atm or 1013 mbar) are also accompanied by elevated temperature (above 100?°C), while lower pressure systems (1-20 mbar) do not require heating.Contents??[/wiki/Ion-mobility_spectrometryhide]?/wiki/Ion-mobility_spectrometry1History/wiki/Ion-mobility_spectrometry2Ion mobility/wiki/Ion-mobility_spectrometry3Instrumentation/wiki/Ion-mobility_spectrometry3.1Ionization/wiki/Ion-mobility_spectrometry3.2Analyzer/wiki/Ion-mobility_spectrometry3.2.1TOFIMS/wiki/Ion-mobility_spectrometry3.2.2DMS/FAIMS/wiki/Ion-mobility_spectrometry3.2.3DMA/wiki/Ion-mobility_spectrometry3.3Drift gas/wiki/Ion-mobility_spectrometry3.4Detector/wiki/Ion-mobility_spectrometry3.5Trapped ion mobility spectrometry/wiki/Ion-mobility_spectrometry4Combined IMS methods/wiki/Ion-mobility_spectrometry4.1GC-IMS?: gas chromatography - ion mobility spectrometry/wiki/Ion-mobility_spectrometry4.2IMS-MS?: ion mobility spectrometry - mass spectrometry/wiki/Ion-mobility_spectrometry4.3LC-IMS?: liquid chromatography - ion mobility spectrometry/wiki/Ion-mobility_spectrometry4.4LC-IMS-MS?: liquid chromatography - ion mobility spectrometry - mass spectrometry/wiki/Ion-mobility_spectrometry5Applications/wiki/Ion-mobility_spec