A Case Report.docVIP

Dent Res J (Isfahan).?2009 Autumn;?6(2): 99–102. PMCID:?PMC3075463 Intraoral Epithelioid Hemangioendothelioma: an Intermediate Vascular Tumor- A Case Report Bhari Sharanesha Manjunatha,*?Gopal Siva Kumar,**?and?Raghunath Vandana*** Author information???Article notes???Copyright and License information?? Go to: Abstract Vascular neoplasms, other than benign are characterized as intermediate or malignant. They are often enshrouded in controversy, because the same neoplasm could show variability in biologic behavior that may not be correlated with microscopic features. The intermediate grade vascular neoplasm is named as epithelioid hemangioendothelioma (EHE). Epithelioid hemangioendothelioma of the oral cavity has been infrequently reported. To the best of our knowledge, the review of the English literature revealed a total of 30 cases of intraoral EHE reported till today. We report such a rare case in a 20 year old male, presented with a growth in lower anterior lingual gingiva since five months before the diagnosis with a history of similar swelling, twice in the same area. The differential diagnosis and brief review of literature is also discussed in the current article. Keywords:?Epithelioid, Hemangioendothelioma, Hemangiosarcoma Go to: Introduction Epithelioid hemangioendothelioma (EHE) is considered as an intermediate vascular neoplasm between hemangioma and angiosarcoma. It is characterized by neoplastic proliferation of epithelioid/histiocytoid endothelial cells.1?Tumors of intermediate behavior have the ability to recur locally and metastasize, but at a far reduced level compared to malignant ones.2 The behavior of oral EHE is not predictable due to lack of agreement in terminology, criteria for diagnosis and difference in biologic behavior relative to its anatomic site and age of occurrence.3Clinically, oral EHE strongly mimics benign reactive lesions such as pyogenic granuloma, chronic periodontal disease, peripheral giant cell granuloma and patients usuall