下呼吸道标中病原菌的分布及耐药性分析.docVIP

下呼吸道标本中病原菌的分布及耐药性分析作者：沈有期 苏丹 丘耿娴 (广东省英德市英城教育东路2号英德市人民医院检验科，广东513000) 关键词：下呼吸道,病原菌,分析 [摘要] 目的： 了解下呼吸道感染患者痰液中的主要病原菌及其耐药性，为临床医生在抗感染治疗时提供合理选用抗生素的信息。 方法： 对2006年1月至2009月12月到我院住院的呼吸道感染患者合格痰液标本进行细菌学培养、鉴定及抗生素敏感试验。 结果： 分离获得298株细菌，G-杆菌占55.4%， 其中以铜绿假单胞菌、肺炎克雷伯氏菌、大肠埃稀氏菌占前3位;G+球菌占26.3%，其中以溶血葡萄球菌、金黄色葡萄球菌、粪肠球菌占前3位;真菌占18.3% ，其中以白色念珠菌为主;药敏结果提示亚安培南对革兰氏阴性杆菌作用最强，革兰氏阳性球菌对万古酶素高度敏感，对其他抗菌药物存在不同程度的耐药。 结论： 下呼吸道感染患者痰液中以革兰氏阴性杆菌引起的感染占优势，白色念珠菌的感染率呈上升趋势，并出现多重耐药，临床医生在抗感染治疗时应根据药敏结果合理选用抗生素进行治疗。 Lower respiratory tract specimens in the distribution of pathogens and drug resistance/Shen youqi,Su dan,Qui gengxian. //Yingde City People’s Hospital, Yingde City, Guangdong Province, City, YingCheng Education East Road No. 2, Yingde,513000 Guangdong. [Abstract] Objective：Sputum in patients with lower respiratory tract infection to understand the main pathogens and their drug resistance, Doctors for clinical anti-infective treatment information to provide reasonable use of antibiotics. Methods：From January 2006 to 2009, 12 months to our hospital for respiratory tract infections in patients with bacteriological culture of qualified sputum specimens, identification and antibiotic susceptibility test. Results：Isolated from 298 bacteria, G-bacilli accounted for 55.4%, of which Pseudomonas aeruginosa, Klebsiella pneumoniae, colon bacteria accounted for Egypt’s pre-diluted 3; G + cocci accounted for 26.3%, of which Staphylococcus haemolyticus, Staphylococcus aureus, fecal Enterococci account for the former three; fungi accounted for 18.3%, of which Candida albicans based; Susceptibility results suggest that the role of imipenem against most gram-negative bacteria, Gram-positive cocci to vancomycin enzyme as highly sensitive to the Other antimicrobial agents have different degrees of resistance. Conclusion：Sputum in patients with lower respiratory tract infections to infections caused by gram-negative bacilli predominated Candida albicans infection rates rise, and the emergence of multi-drug resistance, clinician