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In summary, at present, there is inadequate evidence supporting a causal relation between H pylori gastritis and abdominal symptoms in the absence of ulcer disease. Therefore, cases of abdominal pain consistent with the diagnostic criteria of functional pain (18) should not be investigated for H pylori, unless upper endoscopy is performed during the diagnostic workup in search for organic disease. * The finding of H pylori–associated gastritis in the absence of PUD during diagnostic endoscopy poses a dilemma for the endoscopist (see comment for recommendations 1, 2, and 3). As outlined in the comments for recommendations 1 and 2, there is inadequate evidence supporting a causal relation between H pylori gastritis and abdominal symptoms in the absence of ulcer disease. Therefore, the decision to treat H pylori-associated gastritis without duodenal or gastric ulcer is subject to the judgment of the clinician and deliberations with the patient and family, taking into consideration the potential risks and benefits of the treatment in the individual patient. * The primary goal of testing is to diagnose the cause of clinical symptoms. By definition, a ‘‘test and treat’’ strategy (the detection of the presence of H pylori infection by a noninvasive test followed by treatment in the case of a positive test) will not provide this information in children (see comments on recommendations 1 and 2). * In summary, at present, there is inadequate evidence supporting a causal relation between H pylori gastritis and abdominal symptoms in the absence of ulcer disease. Therefore, cases of abdominal pain consistent with the diagnostic criteria of functional pain (18) should not be investigated for H pylori, unless upper endoscopy is performed during the diagnostic workup in search for organic disease. * The finding of H pylori–associated gastritis in the absence of PUD during diagnostic endoscopy poses a dilemma for the endoscopist (see comment for recommendations 1, 2, and 3). As out
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