2014脑炎课程.pptVIP

脑炎(Encephalitis);中枢神经系统感染(Infections of the nervous system);;分类(Classification);根据侵犯部位分为:;感染途径;感染途径;单纯疱疹病毒性脑炎;Etiology and Pathogenesis;;单纯疱疹病毒（herpes simplex virus,HSV)属ＤＮＡ病毒;Etiology and Pathogenesis;Pathology;因单纯疱疹脑炎死亡的患者的颞叶脑组织标本 A图：血管周围大量炎性细胞浸润：巨噬细胞、淋巴细胞和胶质细胞。B图：高倍视野下小胶质细胞和死亡的神经元细胞;Clinical manifestations;口唇疱疹;Clinical manifestations;Clinical manifestations;Clinical manifestations;Clinical manifestations;Clinical manifestations;Clinical manifestations;Clinical manifestations;Laboratory findings;Laboratory findings; CT scan with contrast of a middle-aged man with a one-week history of a flu-like illness, severe headache and increasing confusion, who had HSV encephalitis confirmed by CSF PCR. (A) A low density area in the left temporal lobe, with swelling and some contrast enhancement. (B) The same patient four days later with more marked changes ;Laboratory findings;;Tour 1: Next/Previous/Start: Herpes Simplex Virus (HSV) encephalitis has its own neuroanatomy. It tends to attack a part of the brain known as the limbic system, a set of interconnected brain structures responsible for the integration of emotion, memory, and complex behavior. This disease is important to recognize because there is an effective drug treatment, acyclovir. ;T2-weighted MRI brain scan showing right temporal lobe hyperintensity in a patient with herpes encephalitis ;Herpes Encephalitis ;HSV或HSV抗原检测;HSV特异性抗体检测;Diagnosis;Diagnosis;Differential Diagnosis;化脓性脑膜炎;急性播散性脑脊髓炎;脑肿瘤;其他病毒学脑炎;Treatment;Treatment;抗病毒药物治疗;肾上腺皮质激素;对症支持治疗;恢复期治疗;Proganosis;Thank you fou your attention !