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Hepatitis B and C乙型和丙型肝炎.docx
Hepatitis B
Definition
Hepatitis B is inflammation of Liver caused by the hepatitis B? HYPERLINK /csr/disease/hepatitis/whocdscsrlyo20022/en/index7.html \l virus virus?(HBV)
HBV is an enveloped? HYPERLINK /csr/disease/hepatitis/whocdscsrlyo20022/en/index7.html \l virus virus?containing a partially double stranded, circular DNA? HYPERLINK /csr/disease/hepatitis/whocdscsrlyo20022/en/index7.html \l genome genome, and classified within the family HYPERLINK /csr/disease/hepatitis/whocdscsrlyo20022/en/index7.html \l hepadnavirus hepadnavirus
Classification
Acute Hepatitis (95%)
Newly acquired infection
Affected individuals notice symptoms approximately 1 to 4 months after exposure to the virus
Symptoms resolve over weeks to months and they are cured of the infection
Chronic Hepatitis (5%)
Hepatitis B virus tests (HBsAg+) are positive after 6 months
Infection with HBV that last longer than 6 month.
Once infected, never go away.
Might progress to develop Liver cirrhosis and hepatocellular carcinoma.
Fatal
The transition from acute hepatitis B to chronic hepatitis B signifies a failure of the immune response to eradicate the virus.
Incubation Period
The incubation period is usually 45-180 days with an average of 60-90 days.
Transmission routes
Blood and blood products
Needle stick injuries
Hepatitis B is highly infectious
Sharing of needles among IV drugs abuser
Sexual contacts
Almost all the body fluids consists the protein
Seminal fluid may contain of the virus
Vertical transmission
Vertical transmission from maternal to child during delivery through the birth canal
Risk Factor
High risk sexual behaviour
Unprotected sex with more than one partner
Unprotected sex with someone whos infected with hbv
Sexual contact with same gender
Share needles during intravenous (IV) drug use
Share a household with someone who has a chronic HBV infection
Occupation exposes to human blood
Contaminated blood products
Contaminated surgical equipment
Receive hemodialysis for e
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