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Online Submissions: World J Gastroenterol 2008 October 14; 14(38): 5781-5788
wjg@ World Journal of Gastroenterology ISSN 1007-9327
doi:10.3748/wjg.14.5781 © 2008 The WJG Press. All rights reserved.
REVIEW
Intrahepatic cholestasis of pregnancy-current achievements
and unsolved problems
Jurate Kondrackiene, Limas Kupcinskas
Jurate Kondrackiene, Limas Kupcinskas, Department of URL: /1007-9327/14/5781.asp DOI:
Gastroenterology, Kaunas University of Medicine, Kaunas /10.3748/wjg.14.5781
50009, Lithuania
Author contributions: Kondrackiene J and Kupcinskas
L contributed equally to this work; Kondrackiene J and
Kupcinskas L wrote the paper based on results of their own
experience and recent literature sources (PubMed, ISI Web of INTRODUCTION
Science) on ICP. Intrahepatic cholestasis of pregnancy (ICP) is the
Correspondence to: Jurate Kondrackiene, MD, PhD,
most common liver disorder unique to pregnancy.
Department of Gastroenterology, Kaunas University of
Medicine, Eiveniu Street 2, Kaunas 50009, ICP predominantly occurs during the third trimester
Lithuania. jukond@takas.l t of pregnancy and characterized by pruritus, and
Telephone: +370-37-326896 Fax: +370-37-326508 biochemical disturbances in liver tests. While ICP poses
Received: April 23, 2008 Revised: June 16, 2008
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