《Pathophysiology and treatment of》.pdfVIP

Pathophysiology and treatment of CKD Prevention of progression and remission/regression strategies for chronic renal disease Piero Ruggenenti, Paolo Cravedi Department of Medicine and Transplantation, Azienda Ospedaliera Ospedali Riuniti CCoorrrreessppoonnddiinngg aauutthhoorr:: Bergamo, Bergamo, Italy Piero Ruggenenti, MD Department of Medicine SSuubbmmiitttteedd:: 10 December 2008 and Transplantation AAcccceepptteedd:: 4 January 2009 Azienda Ospedaliera Ospedali Riuniti Bergamo Arch Med Sci 2009; 5, 3A: S 429–S 434 Largo Barozzi, 1 Copyright © 2009 Termedia Banach 24128 Bergamo, Italy Phone: +39 035 319 888 Fax: +39 035 319 331 E-mail: pruggenenti@ A b s t r a c t ospedaliriuniti.bergamo.it Chronic renal disease (CRD) represents a major health problem, whose dimen- sion is rapidly growing. Chronic nephropathies share common pathogenic me- chanisms that contribute to renal disease progression, even independently of the original cause. Clinical studies found a significant correlation between the rate of G