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Effect of Atorvastatin on Serum Levels of Total Cholesterol and High-Sensitivity C-reactive Protein in High-Risk Patients with Atrial Fibrillation in Asia》.pdf
Clinical Therapeutics/Volume 37, Number 8, 2015 Effect of Atorvastatin on Serum Levels of Total Cholesterol and High-sensitivity C-reactive Protein in High-risk Patients with Atrial Fibrillation in Asia * * Ming Yu Shi, MM ; Feng Hua Xue, BM ; Shi Chao Teng, MM; Li Jiang, MM; Jing Zhu, MM; Feng Yin, MM; and Hong Yue Gu, BM Department of Cardiology, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, P.R. China ABSTRACT Key words: atorvastatin, atrial fibrillation, high- Purpose: The aim of this meta-analysis was to sensitivity C-reactive protein, meta-analysis, serum level, investigate the effects of atorvastatin on serum levels total cholesterol. of high-sensitivity C-reactive protein (hs-CRP) and total cholesterol in atrial fibrillation (AF) patients in Asia. INTRODUCTION Methods: By searching English and Chinese lan- Atrial fibrillation (AF) is the most common type guagebased electronic databases (ie, PubMed, of chronic cardiac arrhythmia and is associated with EBSCO, Ovid, SpringerLink, Wiley, Web of Science, high morbidity and mortality.1 More than 2.3 million Wanfang database, China National Knowledge Infra- Americans have AF, and the number of cases is expected structure, and VIP database), we identified 13 studies to rise to 5.6 million by 2050.2 Approximately 58% of relevant to our topic of interest. Data were collected patients with AF in the western world are older than 75 from the 13 studies and analyzed with Comprehensive years, indicating a significant high-risk age group.3 Risk Meta-Analy
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