Lung Cancer Attributable to Indoor Radon Exposure in France Impact of the.pdfVIP

Research Lung Cancer Attributable to Indoor Radon Exposure in France: Impact of the Risk Models and Uncertainty Analysis Olivier Catelinois,1 Agnès Rogel, 1 Dominique Laurier,1 Solenne Billon,1 Denis Hemon,2 Pierre Verger,3 and Margot Tirmarche 1 1Institute for Radiation Protection and Nuclear Safety, Fontenay-aux-Roses, France; 2French Institute of Health and Medical Research, Villejuif, France; 3Regional Health Observatory Provence Alpes Côte d’Azur, Marseille, France 1999). The second methodologic problem OBJECTIVE: The inhalation of radon, a well-established human carcinogen, is the principal—and involves the role of the uncertainty analysis in omnipresent—source of radioactivity exposure for the general population of most countries. Scientists have thus sought to assess the lung cancer risk associated with indoor radon. Our aim the risk assessment process. Uncertainty here is to assess this risk in France, using all available epidemiologic results and performing an analysis is an essential step that is too seldom uncertainty analysis. performed. METHODS: We examined the exposure–response relations derived from cohorts of miners and from The aim of this study was to assess the joint analyses of residential case–control studies and considered the interaction between radon and lung cancer risk associated with indoor radon tobacco. The exposure data come from measurement campaigns conducted since the beginning of exposure in France on the basis of French the 1980s by the Institute for Radiation Protection a