中药质量评价技术的国内外研究现状及分析.pdfVIP

中药与临床 harmacy and Clinics of ChineseM ateriaM edica 2011; 2( 2) 59 综述进展 中药质量评价技术的国内外研究现状及分析 1 2 陶燕蓉, 陈曦 [] :分析中药质量评价研究现状, 探讨中药质量评价的方法发展趋势: 查阅近年有 中药质量评价相 文献, 通过分析归纳与综合进行评述: 目前中药质量控制主流仍然是以化学成分为中心的质量控制, 但由于其在 中药质量控制中所显示出的局限性, 多种替代方法应运而生, 并均表现出 一定的优势: 对具多成分特点的中药, 从生 物活性特征出发建立适合中药质量控制的新方法不仅必要, 而且完全可行 [] 中药质量; 评价技术; 生物活性; Caco- 2单层细胞模型;指纹图谱 [] R 2- 031 [] A [ ] 1674- 926X( 2011) 01- 0059- 04 Current status ofTraditionalChineseMedicine(TCM ) quality evaluation methods at home and a 1 2 broad/TAO Yanrong , CHEN X i // (1. Dong ZhMi enH osp ital of eking TCM University, Beij ing 100101, Chi na; 2. Institute of M edicinal lantD evelopm ent, ChineseA cademy of M edical Science and eking Union M edical College, Beijing 100193, China) [Abstract] bjective: To analyze t e current status and discuss t e development trend of Traditional C i neseM ed icine(TCM ) quality evaluation met ods. M ethod: Related L iteratures w ere researc ed in recent years and review ed by analysis, induction and synt esis. Result: T emainstream ofTCM quality control based on c em i cal constituent at present. Because of its lmi itation, ot er superior substitute met ods ad appeared. Conclusion: Because of t e comp licated composition ofTCM, it is necessary and feasible to establis some new met odsw ic are su itable forTCM quality control based on biological activity c aracters. T ese met ods w ill ave broad pros pects. [Key words] TCM quality; evaluation met od; biological activity; Caco- 2 cellmonolayermode;l fingerprint 1 () , , () , ,