光敏剂漂白特性的研究.pdfVIP

4 2 1 100081 2 200030 532nm HMME HMME Study on the Photobleaching Properties of HMME 1 2 YU Changqing JIANG Wei 1 Department of Photonics Engineering, Beijing Institute of Technology, 100081 2 Department of Physics, Shanghai Jiaotong University, 200030 Abstract: A photobleaching and fluorescence spectra detecting system was setup for study the photobleaching properties and the changing of fluorescence spectrum of Hematoporphyrin Monomethyl Ether (HMME) solution. A power tunable CW 532nm laser was used both as photobleaching light source and fluorescence exciting source. The results showed that the curve of fluorescence intensity of HMME solution vs illuminating time should be fitted by the second order of exponential decay equation which has tow photobleaching time. We consider the longer time to the photosensitizers bonded together, and the shorter one related to the isolated molecules. There is a new fluorescence peak emerge out while the photobleaching time passing. A new material produced by photobliching may emit this new fluorescence peak. Keywords: Photosensitizer, Photobleaching, Fluorescence spectra. (Photodynamic Therapy, PDT)