高度近视眼的血流动力学研究.docVIP

高度近视眼的血流动力学研究 作者：肖满意　黄溥倪　姜德咏　周启昌 单位：湖南医科大学附属第二医院　湖南长沙　410011 关键词：高度近视眼；超声检查；彩色多谱勒 【摘要】为了研究高度近视眼血流动力学变化，应用彩色多谱勒血流仪检测35例高度近视眼和30例正常的眼动脉、睫状后短动脉及视网膜中央动脉的血流参数；测定收缩期血流峰值速度、舒张末期血流速度、时间相关的平均最大血流速度、搏动指数、阻力指数及收缩期血流峰值速度和舒张末期血流速度比值。结果显示：高度近视眼的视网膜中央动脉及睫状后短动脉血流速度低于正常人组(P＜0.01)，血管阻力高于正常人组(P＜0.05)；高度近视眼的眼动脉各血流参数与正常人比较，差异无显著性(P＞0.05)。说明眼部供血不足可能是引起高度近视眼视网膜、脉络膜进行性病理改变的原因。［中图分类号］R778.1＋1；R445.1　　［文献标识码］A［文章编号］1008-1372(2000)09-0525-03 Color Doppler Imaging Analysis of Ocular Hemodynamics in Excessive Myopia XIAO Man-yi,HUANG Pu-ni,JIANG De-yong,et al.(Department of Ophthalmology,The Second Affiliated Hospital,Hunan Medical University,Changsha,410011,China) 【Abstract】To understand the etiological mechanism of binocular damage in excessive myopia,the ocular hemodynamics of thirty-five patients with excessive myopia and thirty normal controls were determined by using color doppler blood flow imaging.Then the peak systolic velocity(Vtmax),the end diastolic velocity(Vmin),the time averaged maximum velocity(Vmax),the pules index(PI),the resistance index(RI) and S/D(Vmax/Vmin)of the ophthalmic artery(OA),the short posterior ciliary artery(SPCA) and the central retinal artery(CRA) were compared in the two groups.The results were as follows;Compared with the normal subjects,the patients with excessive myopia showed a decreased blood flow velocity in the short posterior ciliary arteries and the central retinal artery(P＜0.01),and an increased PI,RI and S/D(P＜0.05);all six blood flow parameters of OA in the two groups were not significantly different from each other(P＞0.05).These findings suggest that the blood-supply deficiency of binoculus in excessive myopia could cause the progressive lesion of retinas and chorioids of the patients.Key Words　Excessive myopia;Ultrasonography;Color doppler 　　高度近视眼(excessive myopia)是指轴性近视超过6.00D者，其临床特点为患者中年之后，眼底出现种种退行性变性，这种变性能够导致各种并发症的发生，但其确切病因及发病机理尚无定论［1］。我们应用彩色多谱勒血流仪(color doppler imaging,CDI)检测30例正常人(60只眼)及35例(65只眼)高度近视眼患者的视网膜中央动脉(central retinal artery,CR