温度_pH敏感性接枝共聚物水凝胶P_DMAEMA_g_NIPAM_合成及性质研.pdfVIP

2009 年第67 卷 化 学 学 报 Vol. 67, 2009 第16 期, 1910～1916 ACTA CHIMICA SINICA No. 16, 1910～1916 ·研究论文· 温度/pH 敏感性接枝共聚物水凝胶 P(DMAEMA-g-NIPAM)的 合成及性质研究 刘守信* 张朝阳 房 喻 王焕霞 陈奋强 (应用表面与胶体化学教育部重点实验室 陕西师范大学化学与材料科学学院 西安 710062) 摘要 利用大分子单体技术, 采用自由基溶液聚合合成了温度/pH 敏感性聚甲基丙烯酸-N,N-二甲氨基乙酯接枝聚N-异 丙基丙烯酰胺[P(DMAEMA-g-NIPAM)]水凝胶. 用红外光谱及扫描电镜对凝胶的组成及形貌进行了表征. 凝胶的去溶 胀和溶胀动力学研究表明, 所合成的凝胶具有温度和 pH 敏感性. 与传统的聚丙烯酸系水凝胶相比, P(DMAEMA-g- NIPAM) 具有相反的 pH 敏感性; P(DMAEMA-g-NIPAM)凝胶在 55 ℃时具有较快的去溶胀速率, 随着凝胶中接枝链 PNIPAM 量的增加, 凝胶的去溶胀速率加快. 关键词 甲基丙烯酸-N,N-二甲氨基乙酯; N-异丙基丙烯酰胺; 接枝水凝胶 Synthesis and Characterization of Temperature- and pH-sensitive Poly[2-(N,N-dimethylamino)ethyl methacrylate-g-N- isopropylacrylamide] Hydrogels Liu, Shouxin* Zhang, Zhaoyang Fang, Yu Wang, Huanxia Chen, Fenqiang (Key Laboratory of Applied Surface and Colloid Chemistry of Ministry of Education, School of Chemistry and Materials Science, Shaanxi Normal University, Xian 710062 ) Abstract A novel temperature- and pH-sensitive graft copolymer hydrogel composed of 2-(N,N- dimethylamino)ethyl methacrylate (DMAEMA) and N-isopropylacrylamide (NIPAM) was synthesized by macromonomer technique and free radical solution polymerization. The composition and surface morphol- ogy of the hydrogels were investigated by means of Fourier transform infrared spectroscopy and scanning electron microscopy. The deswelling and swelling kinetics of the graft copolymer hydrogels in different pH media at different t